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The Efficacy of Shinbaro for the Preventive Treatment of Migraine: A Pilot Study
المؤلفون المشاركون
Jung, Yesol
Won, Bohee
Lee, Mijung
Chung, Jinyoung
Han, Sung Ju
Kim, Manho
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-13
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the therapeutic potential and efficacy of Shinbaro, an herbal medication for inflammatory diseases and bone disorders, as a preventive treatment of migraine.
Methods.
In this prospective, interventional, single-arm, pre-post study, 37 migraine patients took 600mg bid of Shinbaro for 12 weeks.
At 4-week intervals, the migraine frequency and the rescue medications frequency were measured from each patient’s headache diary.
The modified Migraine Disability Assessment (MIDAS) questionnaires to assess migraine associated disabilities were also completed at each visit.
The serum calcitonin gene-related peptide (CGRP) concentrations before and after 12 weeks of Shinbaro administration were compared.
Results.
The monthly migraine frequency was significantly reduced from 20.5 days at baseline to 16.4 days at week 12 (P =0.003), and 22% of the participants showed ≥ 50% reduction.
The frequency reduction was observed by week 4 (P =0.035) and continuously occurred through week 8 (P =0.001) and week 12 (P =0.003).
The rescue medications frequency also decreased significantly from 17.4 days at baseline to 13.2 days at week 12 (P =0.035).
Lastly, the serum CGRP concentration dropped from 434.6 pg/mL at baseline to 371.4 pg/mL at week 12, which was statistically significant (P <0.001).
Conclusions.
Shinbaro demonstrated prophylactic effects in migraine patients, significantly reducing their mean migraine frequency, rescue medications frequency, and the serum CGRP concentration after 12 weeks of treatment.
This study is registered in Clinical Research Information Service, Seoul National University Hospital Clinical Research Institute (IRB No.
1604-138-758).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jung, Yesol& Won, Bohee& Lee, Mijung& Chung, Jinyoung& Han, Sung Ju& Kim, Manho. 2019. The Efficacy of Shinbaro for the Preventive Treatment of Migraine: A Pilot Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1148909
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jung, Yesol…[et al.]. The Efficacy of Shinbaro for the Preventive Treatment of Migraine: A Pilot Study. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1148909
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jung, Yesol& Won, Bohee& Lee, Mijung& Chung, Jinyoung& Han, Sung Ju& Kim, Manho. The Efficacy of Shinbaro for the Preventive Treatment of Migraine: A Pilot Study. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1148909
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148909
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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