Early Aggressive Immunotherapy Improves Functional Outcome in Chronic Immune Sensory Polyradiculopathy
المؤلفون المشاركون
Koh, Jasmine Shimin
Tung, James Wei Min
Tan-Yu, Genevieve Lynn Yu
Umapathi, Thirugnanam
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-21
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Chronic immune sensory polyradiculopathy (CISP) is an uncommon and treatable inflammatory disorder of the proximal sensory nerve roots.
Patients typically present with severe sensory ataxia, normal motor examination, unsteady gait, and normal nerve conduction studies (NCS).
We describe an elderly man who presented with a two-week history of progressive numbness of both legs and recurrent falls.
He had hyporeflexia, normal strength, severe proprioceptive, and vibration sense loss in both lower limbs and was unable to stand or walk because of severe sensory ataxia.
The NCS and MR scan of the spine were normal.
Tibial somatosensory evoked potentials revealed proximal conduction defect and localized the pathology to the lumbar sensory nerve roots proximal to the dorsal root ganglion.
Cerebrospinal fluid showed cytoalbuminergic dissociation suggestive of inflammation.
CISP was diagnosed; he was given aggressive immunotherapy consisting sequentially of corticosteroids with mycophenolate mofetil and three cycles of intravenous immunoglobulin after which he regained independent mobility.
Unlike previous reports where patients presented months-years after symptom onset and improved after single-line immunotherapy, our patient presented fairly acutely and made dramatic improvement only after aggressive combination therapy.
We urge physicians to recognize this uncommon neurologic cause of sensory ataxia where early aggressive treatment is crucial for better functional outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Koh, Jasmine Shimin& Tung, James Wei Min& Tan-Yu, Genevieve Lynn Yu& Umapathi, Thirugnanam. 2020. Early Aggressive Immunotherapy Improves Functional Outcome in Chronic Immune Sensory Polyradiculopathy. Case Reports in Neurological Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148931
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Koh, Jasmine Shimin…[et al.]. Early Aggressive Immunotherapy Improves Functional Outcome in Chronic Immune Sensory Polyradiculopathy. Case Reports in Neurological Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1148931
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Koh, Jasmine Shimin& Tung, James Wei Min& Tan-Yu, Genevieve Lynn Yu& Umapathi, Thirugnanam. Early Aggressive Immunotherapy Improves Functional Outcome in Chronic Immune Sensory Polyradiculopathy. Case Reports in Neurological Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148931
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148931
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر