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Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa Essential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity
المؤلفون المشاركون
Almeida-Souza, Fernando
Teles, Amanda Mara
Rosa, Taynan Dulce da Silva
Mouchrek, Adenilde Nascimento
Abreu-Silva, Ana Lúcia
Calabrese, Kátia da Silva
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-15
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The resistance mechanisms of bacteria and protozoans have evidenced the need of discover new compounds with potential pharmaceutical activity against pathogenic microorganisms.
Medicinal plants have been for centuries a promising alternative as sources of new drugs.
The objective of this work was to evaluate the chemical composition, antimicrobial and antileishmanial activities of Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa essential oils.
Chemical analysis was performed by gas chromatography-mass spectrometry.
Antimicrobial activity was performed by disk diffusion and minimum inhibitory concentration (MIC) test.
Antileishmanial activity was performed against antipromastigote and intracellular amastigote of Leishmania amazonensis.
Cytotoxic and nitrite production were realized in BALB/c peritoneal macrophages.
The major compounds of the essential oils were cinnamic aldehyde (46.30%) in C.
zeylanicum, cis-p-menth-2-en-1-ol (33.88%) and linalyl acetate (13.90%) in O.
vulgare, and turmerone (55.43%) in C.
longa.
The MIC showed significant antimicrobial activity of C.
longa essential oil against S.
aureus (83.3 ± 14.43 µg/mL).
Antipromastigote activity showed IC50 values >500 µg/mL to C.
zeylanicum, 308.4 ± 1.402 µg/mL to O.
vulgare, and 405.5 ± 1.119 µg/mL to C.
longa essential oil.
Activity against intracellular amastigote of L.
amazonensis showed IC50 of 63.3 ± 1.369 µg/mL and cytotoxic was not observed, resulting in selectivity index higher than 15.79 to parasite.
C.
longa essential oil decreased nitrite production in peritoneal macrophages, but not in Leishmania-infected cells.
The chemical composition of the three essential oils is directly associated to its potential biological action, as the antimicrobial activity.
C.
longa presented a potent antileishmanial activity against promastigote and intracellular amastigote of L.
amazonensis, although this activity is not linked to nitric oxide, since C.
longa essential oil inhibits its production.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Teles, Amanda Mara& Rosa, Taynan Dulce da Silva& Mouchrek, Adenilde Nascimento& Abreu-Silva, Ana Lúcia& Calabrese, Kátia da Silva& Almeida-Souza, Fernando. 2019. Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa Essential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148940
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Teles, Amanda Mara…[et al.]. Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa Essential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1148940
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Teles, Amanda Mara& Rosa, Taynan Dulce da Silva& Mouchrek, Adenilde Nascimento& Abreu-Silva, Ana Lúcia& Calabrese, Kátia da Silva& Almeida-Souza, Fernando. Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa Essential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148940
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148940
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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