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LipomatousExtensively Vacuolated Ependymoma with Signet-Ring Cell-Like Appearance: Analysis of a Case with Extensive Literature Review
المؤلفون المشاركون
Salinas-Lara, Citlaltepetl
Ortiz-Plata, Alma
Tena-Suck, Martha Lilia
Salazar, Miguel Fdo.
Rembao-Bojórquez, Daniel
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-14
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
“Lipomatous” and “extensively vacuolated” are descriptive captions that have been used to portray a curious subset of ependymomas distinctively bearing cells with a large vacuole pushing the nucleus to the periphery and, thus, simulating a signet-ring cell appearance.
Here, we would like to report the first ependymoma of this kind in a Latin American institution.
A 16-year-old boy experienced cephalea during three months.
Magnetic resonance imaging scans showed a left paraventricular tumour which corresponded to anaplastic ependymoma.
Intriguingly, it was also composed of cells with single or multiple hollow cytoplasmic vacuoles sometimes giving a signet-ring cell-like configuration.
Immunolabeling of these showed membrane positivity for GFAP, PS100, and CD99, while Ki-67 expression was null.
Ultrastructural examination of retrieved paraffin-embedded tissue showed the presence of scarce microlumina filled with microvilli but failed to demonstrate any content in such optically empty vacuoles as only scant granulofibrillary debris was observed.
A schism prevails at present regarding these unusual morphological variants, being either “lipomatous” or “vacuolated” based mainly on the EMA immunoprofile.
This, however, is a misappropriate approaching.
Could it be that perhaps we are dealing with the same histopathological entity or it may simply happen that fixation and artefacts cannot allow for their proper identification?
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salazar, Miguel Fdo.& Tena-Suck, Martha Lilia& Ortiz-Plata, Alma& Salinas-Lara, Citlaltepetl& Rembao-Bojórquez, Daniel. 2017. LipomatousExtensively Vacuolated Ependymoma with Signet-Ring Cell-Like Appearance: Analysis of a Case with Extensive Literature Review. Case Reports in Pathology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1149085
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salazar, Miguel Fdo.…[et al.]. LipomatousExtensively Vacuolated Ependymoma with Signet-Ring Cell-Like Appearance: Analysis of a Case with Extensive Literature Review. Case Reports in Pathology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1149085
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salazar, Miguel Fdo.& Tena-Suck, Martha Lilia& Ortiz-Plata, Alma& Salinas-Lara, Citlaltepetl& Rembao-Bojórquez, Daniel. LipomatousExtensively Vacuolated Ependymoma with Signet-Ring Cell-Like Appearance: Analysis of a Case with Extensive Literature Review. Case Reports in Pathology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1149085
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149085
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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