Successful Treatment of Severe Atopic Dermatitis with Calcitriol and Paricalcitol in an 8-Year-Old Girl
المؤلفون المشاركون
Bothou, Christina
Alexopoulos, Alexis
Dermitzaki, Eleni
Kleanthous, Kleanthis
Papadimitriou, Anastasios
Mastorakos, George
Papadimitriou, D. T.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-24
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Atopic dermatitis (AD) is a chronic inflammatory disease affecting children and adolescence.
The traditional therapeutic options for AD, including emollients topically and immune modulatory agents systemically focusing on reducing skin inflammation and restoring the function of the epidermal barrier, are proven ineffective in many cases.
Several studies have linked vitamin D supplementation with either a decreased risk to develop AD or a clinical improvement of the symptoms of AD patients.
In this report, we present a girl with severe AD who under adequate supplementation with cholecalciferol was treated with calcitriol and subsequently with paricalcitol.
She had significant improvement—almost healing of her skin lesions within 2 months, a result sustained for more than 3 years now.
Because of hypercalciuria as a side effect from calcitriol therapy, treatment was continued with paricalcitol, a vitamin D analogue used in secondary hyperparathyroidism in chronic kidney disease.
Calcitriol therapy may be considered as a safe and efficacious treatment option for patients with severe AD, particularly for those with refractory AD, under monitoring for possible side effects.
Treatment with paricalcitol resolves hypercalciuria, is safe, and should be further investigated as an alternative treatment of atopic dermatitis and possibly other diseases of autoimmune origin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bothou, Christina& Alexopoulos, Alexis& Dermitzaki, Eleni& Kleanthous, Kleanthis& Papadimitriou, Anastasios& Mastorakos, George…[et al.]. 2018. Successful Treatment of Severe Atopic Dermatitis with Calcitriol and Paricalcitol in an 8-Year-Old Girl. Case Reports in Pediatrics،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1149290
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bothou, Christina…[et al.]. Successful Treatment of Severe Atopic Dermatitis with Calcitriol and Paricalcitol in an 8-Year-Old Girl. Case Reports in Pediatrics No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1149290
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bothou, Christina& Alexopoulos, Alexis& Dermitzaki, Eleni& Kleanthous, Kleanthis& Papadimitriou, Anastasios& Mastorakos, George…[et al.]. Successful Treatment of Severe Atopic Dermatitis with Calcitriol and Paricalcitol in an 8-Year-Old Girl. Case Reports in Pediatrics. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1149290
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149290
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر