Osteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome

الملخص EN

Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder caused by insufficient expression of the TCF4 gene.

Children with PTHS typically present with gastrointestinal disorders and early severe chronic constipation is frequently found (75%).

Here we describe the case of a PTHS male 10-year-old patient with chronic constipation in whom Osteopathic Manipulative Treatment (OMT) resulted in improved bowel functions, as assessed by the diary, the QPGS-Form A Section C questionnaire, and the Paediatric Bristol Stool Form Scale.

The authors suggested that OMT may be a valid tool to improve the defecation frequency and reduce enema administration in PTHS patients.