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Comparative Study of Crude and Wine-Processing Corni Fructus on Chemical Composition and Antidiabetic Effects
المؤلفون المشاركون
Bi, Huailong
Niu, Dou
Guo, Chen
Li, Jia
Chen, Xue
Zhang, Yuan
Wang, Shaojun
Bai, Jiqing
Li, Xing
Kang, Jiefang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Wine processing is a specialized technology which involves sautéing crude herbal medicine using Chinese rice wine.
Herein, we identified the changes in chemical profiles and antidiabetic effects of Corni Fructus (CF) after wine processing in high-fat diet (HFD) streptozotocin- (STZ-) induced diabetic mice.
A novel high-efficiency method for simultaneously quantifying gallic acid, 5-hydroxymethylfurfural, morroniside, loganin, sweroside, and cornuside by UPLC was developed, and validating crude and wine-processing CF was done for the first time.
Mice were randomly divided into the following groups and orally given different solutions for 4 weeks: normal group (NC, 0.4% (w/v) CMC-Na), model group (DM, 0.4% (w/v) CMC-Na), crude CF group (CP, 3.87 g/kg), and wine-processing CF group (PP, 3.87 g/kg) followed by HFD and multiple subcutaneous injection of STZ (40 mg/kg) to induce the diabetes model except the NC group.
Biochemical indexes (body weight, fasting blood glucose level, lipid level, insulin, and free fatty acid) and other parameters involving liver toxicity were measured with commercial kits and immunohistochemical method.
Comparative studies on pharmacology showed that the crude extracts possess higher efficacy on hypoglycemia and hypolipidemia, while wine-processing products exhibit better effects on liver preservation.
Our data suggested that wine processing was recommended when CF was used for protecting the liver; however, crude products should be used as antidiabetic drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bi, Huailong& Niu, Dou& Guo, Chen& Li, Jia& Chen, Xue& Zhang, Yuan…[et al.]. 2019. Comparative Study of Crude and Wine-Processing Corni Fructus on Chemical Composition and Antidiabetic Effects. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1149682
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bi, Huailong…[et al.]. Comparative Study of Crude and Wine-Processing Corni Fructus on Chemical Composition and Antidiabetic Effects. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1149682
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bi, Huailong& Niu, Dou& Guo, Chen& Li, Jia& Chen, Xue& Zhang, Yuan…[et al.]. Comparative Study of Crude and Wine-Processing Corni Fructus on Chemical Composition and Antidiabetic Effects. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1149682
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149682
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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