Simultaneous Presentation of Uveitic Disc Edema and Papilledema in an Adult

الملخص EN

Purpose.

To present a case of simultaneous uveitic disc edema and increased intracranial pressure (IICP) in an adult.

Methods.

Retrospective case report.

Patients.

A 29-year-old woman affected by bilateral optic disc edema from bilateral posterior uveitis complicated by IICP with papilledema.

Results.

Laboratory workup was negative for infectious and systemic inflammatory causes of uveitis.

Computed Tomography scan of the chest was negative for Sarcoidosis.

Magnetic Resonance Imaging of the brain and orbits revealed a partially empty sella, bilateral posterior globe flattening without optic nerve sheath enhancement, masses, white matter lesions, or meningeal enhancement.

Cerebral Magnetic Resonance Venography showed narrowing of the right and left transverse sinuses without thromboses.

Prednisone was initiated for the uveitis which improved the vision but caused weight gain.

Neurology evaluation with a lumbar puncture in the lateral decubitus position revealed elevated opening pressure and otherwise normal cerebrospinal fluid.

Ocular ultrasonography was considered but not available to measure optic nerve sheath diameter.

Oral acetazolamide 1000 mg twice daily was started for papilledema as prednisone was tapered.

Periocular steroid and intravitreal bevacizumab injections were used for sight threatening cystoid macular edema and choroidal neovascularization, respectively.

Discussion.

While previously described in children, we report the first known case of bilateral uveitic disc edema and papilledema in an adult.

This report will discuss recommendations for evaluation of these rarely concurrent conditions and therapy for both uveitic disc edema and papilledema.