Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model
المؤلفون المشاركون
Ronghua, Zhao
Bao, Yanyan
Mao, Xin
Yao, Rongmei
Guo, Shanshan
Bao, Lei
Gao, Yingjie
Shi, Yujing
Cui, Xiaolan
Sun, Jing
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-10
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Cervicitis is a common sexually transmitted disease.
In recent years, the abuse of antibiotic in the treatment of cervicitis results in the emergence of antibiotic-resistant bacteria; alternative strategies are needed to be developed.
In this research, we investigated the effects of Feilin Vaginal Gel (FVG), a Chinese herbal formula, on the treatment of cervicitis.
Two cervicitis models were optimized using BALB/c mouse; one in vitro model was established in HeLa cells.
In Chlamydia trachomatis-induced cervicitis model, the high level of bacterial loads, the inflammation in tissue, and the cytokines in serum could be observed.
With the administration of FVG, the bacterial loads in cervical mucus and cervix tissue could be significantly inhibited in dose-dependent manners.
The pathological injury of cervix and vagina, as well as the levels of IL-2, IL-17, and MCP-1 in serum, could be mitigated by FVG.
FVG reduced the number of inclusion induced by C.
trachomatis in HeLa cells.
In addition, the histological damage in Escherichia coli and Staphylococcus aureus-induced cervicitis model could be reduced by FVG.
These results suggest that FVG is capable of treating cervicitis through the inhibition of pathogens and the regulation of host immune responses.
FVG may contribute as an alternative agent for the treatment of cervicitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mao, Xin& Ronghua, Zhao& Yao, Rongmei& Guo, Shanshan& Bao, Lei& Gao, Yingjie…[et al.]. 2019. Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1149730
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mao, Xin…[et al.]. Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1149730
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mao, Xin& Ronghua, Zhao& Yao, Rongmei& Guo, Shanshan& Bao, Lei& Gao, Yingjie…[et al.]. Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1149730
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149730
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر