Ligustrum robustum Intake, Weight Loss, and Gut Microbiota: An Intervention Trial
المؤلفون المشاركون
Chen, Jiayi
Liu, Sijing
Pei, Xiaofang
Zhou, Tao
Chen, Yuhang
Xu, Jiayi
Zheng, Tianli
Sun, Dianjianyi
Qi, Lu
Xiong, Jingyuan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-14
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Ligustrum robustum (LR) shows antiobesity effects in animal studies.
However, little is known about the effect on human.
The present study aimed to investigate the effect of LR intake on weight change in obese women and the role of gut microbiota.
Thirty overweight and obese female participants (BMI ≥24 kg/m2) were recruited in the current study.
The participants drank LR 10g/d for 12 wks.
Their body composition and related biomarkers were assessed.
Alterations of the gut microbiota were analyzed using 16S rRNA sequencing.
The primary outcome was the change in body weight.
LR intake resulted in 2.5% weight loss over 12 wks (P<0.01).
Change in body fat at 12 wk was -1.77 ± 1.19 kg (P<0.01).
In addition, decreased Firmicutes-to-Bacteroidetes ratio (P=0.03), increased richness (the ACE estimator, P<0.01; the Chao1 estimator, P<0.01), and altered representative taxa of the gut microbiota were observed.
Bacteroidaceae, Bacteroides, Bacilli, and Lactobacillales were higher while Ruminococcaceae, Enterobacteriaceae, Enterobacteriales, Lachnospiraceae, Clostridia, and Clostridiales were lower at 12 wk.
Moreover, LR intervention decreased fasting glucose (P<0.01), serum leptin (P<0.01), and IL8 (P=0.02) and increased HOMA-β (P<0.01).
LR intervention moderately decreased the body weight in overweight and obese women and such effect might be due to modulation of gut microbiota.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Tao& Chen, Jiayi& Chen, Yuhang& Xu, Jiayi& Liu, Sijing& Zheng, Tianli…[et al.]. 2019. Ligustrum robustum Intake, Weight Loss, and Gut Microbiota: An Intervention Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1149872
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Tao…[et al.]. Ligustrum robustum Intake, Weight Loss, and Gut Microbiota: An Intervention Trial. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1149872
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Tao& Chen, Jiayi& Chen, Yuhang& Xu, Jiayi& Liu, Sijing& Zheng, Tianli…[et al.]. Ligustrum robustum Intake, Weight Loss, and Gut Microbiota: An Intervention Trial. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1149872
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149872
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر