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Thoracic Paravertebral Mass as an Infrequent Manifestation of IgG4-Related Disease
المؤلفون المشاركون
Rubin, Bernard
Meysami, Alireza
Matzumura Kuan, Melissa
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-28
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Case.
A 50-year-old African American male presented with abdominal pain and significant weight loss.
On physical examination, he had parotid and submandibular gland enlargement associated with right eye proptosis.
Computed tomography showed a thoracic paravertebral soft tissue mass, enlarged lymph nodes, and ascending aortic aneurysm.
Laboratory results were remarkable for elevated total IgG and IgG4 subclass.
The submandibular gland pathology revealed chronic sclerosing sialadenitis, with a large subset of inflammatory cells positively staining for IgG4.
The histology of the paravertebral mass demonstrated fibrosclerosis with increased lymphocytic infiltrate, associated with increased IgG4 plasma cells.
He was diagnosed with immunoglobulin G4-related disease (IgG4-RD).
Steroid therapy initially yielded improvement; however, after steroids were stopped, there was disease recurrence.
Prednisone was restarted, and the plan was to start him on rituximab.
Interestingly, the patient’s brother also had IgG4-RD.
Conclusion.
IgG4-RD can present as a paravertebral mass which is usually responsive to steroids; however, recurrent and resistant disease can be seen for which steroid-sparing agents such as rituximab should be considered.
In addition, to the best of our knowledge, this is the first reported case of IgG4-RD in two family members presenting as a paravertebral mass, highlighting an exciting area for more research in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matzumura Kuan, Melissa& Rubin, Bernard& Meysami, Alireza. 2017. Thoracic Paravertebral Mass as an Infrequent Manifestation of IgG4-Related Disease. Case Reports in Rheumatology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1149957
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matzumura Kuan, Melissa…[et al.]. Thoracic Paravertebral Mass as an Infrequent Manifestation of IgG4-Related Disease. Case Reports in Rheumatology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1149957
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matzumura Kuan, Melissa& Rubin, Bernard& Meysami, Alireza. Thoracic Paravertebral Mass as an Infrequent Manifestation of IgG4-Related Disease. Case Reports in Rheumatology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1149957
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149957
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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