Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody

الملخص EN

Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs.

We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5–2 years and developed recurrent pericardial effusion as a result of it.

Initially her condition was managed with a pericardial window.

The recurrence of a massive pericardial effusion necessitated a right hemipericardiectomy.

After hydralazine was stopped, she never had any further episodes of pericardial effusion or tamponade.