Antipruritic Effect of Qingpeng Ointment on the Localized Nonexudative Eczema
المؤلفون المشاركون
Li, Lin-Feng
Zhang, Rui-na
Li, Yan
Xu, Wei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the effectiveness and safety of Qingpeng ointment on eczema-associated pruritus.
Trial Design and Method.
This single center randomized double-blinded placebo-controlled trial enrolled 60 patients with nonexudative eczema, who were randomized at 1:1 ratio to the Qingpeng ointment and placebo control groups (n=30 in each group).
The investigational and control ointment were applied on lesions twice daily for two weeks.
Visual analogue scale (VAS) and pruritus symptom scores were used to assess pruritus severity, frequency, and duration.
Eczema lesions were evaluated by eczema area and severity index (EASI) and lesion morphology scores.
Subjects were evaluated after the first treatment and at the end of the first and second week.
Results.
The average age and disease duration were 50.1±13.5 years and 30.9±16.0 weeks, respectively.
Baseline EASI and VAS scores were similar between the two groups.
VAS scores of the Qingpeng ointment group were significantly lower than those of the placebo control group at 10 minutes and 30 minutes after the first treatment and the first and second week follow-up (all P < 0.05).
The scores of pruritus severity, frequency, and duration were significantly lower in the Qingpeng ointment group than in the control group at the end of week 1 and week 2 of the study (all P < 0.05).
The scores of lesion morphology at the end of week 1 of the study were not significantly different between the two groups, but the Qingpeng ointment group showed significantly lower score than the placebo control group at the end of week 2 of the study.
No adverse event was observed in the study.
Conclusion.
Qingpeng ointment can effectively alleviate pruritus and reduce skin lesions in patients with nonexudative eczema.
The antipruritic effects occurred early and at a greater magnitude than the effects on lesion attenuation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yan& Xu, Wei& Li, Lin-Feng& Zhang, Rui-na. 2019. Antipruritic Effect of Qingpeng Ointment on the Localized Nonexudative Eczema. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1149978
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yan…[et al.]. Antipruritic Effect of Qingpeng Ointment on the Localized Nonexudative Eczema. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1149978
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yan& Xu, Wei& Li, Lin-Feng& Zhang, Rui-na. Antipruritic Effect of Qingpeng Ointment on the Localized Nonexudative Eczema. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1149978
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1149978
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر