The Child as a Surrogate for Diagnosis of Lupus in the Mother

الملخص EN

Introduction.

Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies.

Methodology.

This is a case report of a male infant delivered via Caesarean section at 36-week gestation following detection of fetal bradycardia during routine antenatal clinic visit.

Results.

The mother was seropositive for antinuclear antibody (ANA) and anti-Ro/SSA and had elevated erythrocyte sedimentation rate.

The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA.

Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block.