Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats
المؤلفون المشاركون
Jiang, Jiaye
Huang, Dan
Li, Yuan
Gan, Zhongyuan
Li, Hanqing
Li, Xindan
Bian, Ka
Ke, Yan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-16
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Modern research has shown that BanXia BaiZhu TianMa decoction (BBT) has the potential effect of lowering BP in vitro and in vivo.
However, its therapeutic mechanism has not been clearly defined.
The present study was designed to evaluate the protective effect of BBT on the heart by examining heart functioning and anti-inflammatory characteristics and to obtain scientific evidence for its further medical applications.
BBT was extracted by decocting the herb extraction and analysed by HPLC.
The left ventricular mass index (LVMI) was measured, and a histological examination of samples of the heart was performed.
Inflammatory status was investigated by measuring tissue levels of interleukin-1 (IL-1), interleukin-6 (IL-6), tumour necrosis factor (TNF-α), inducible nitric oxide synthase (iNOS), and molecules of the nuclear factor κB (NF-κB) pathway.
The BBT treatment significantly reversed the course of hypertension-derived heart damage.
Meanwhile, the herb formula markedly reduced levels of IL-1, IL-6, TNF-α, and iNOS.
In addition, the traditional compound suppressed the activity of the NF-κB pathway.
The present study provides evidence of heart protection by BBT in SHRs.
The action mechanisms may be partially attributable to the anti-inflammatory characteristic of the formula.
Understanding the pharmacological action of BBT will benefit its impending use.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jiang, Jiaye& Huang, Dan& Li, Yuan& Gan, Zhongyuan& Li, Hanqing& Li, Xindan…[et al.]. 2019. Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150175
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jiang, Jiaye…[et al.]. Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1150175
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jiang, Jiaye& Huang, Dan& Li, Yuan& Gan, Zhongyuan& Li, Hanqing& Li, Xindan…[et al.]. Heart Protection by Herb Formula BanXia BaiZhu TianMa Decoction in Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150175
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1150175
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر