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Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice
المؤلفون المشاركون
Kang, Changkeun
Kong, Joo-Yeon
Yeon, Seong-Chan
Lee, Hu Jang
Park, Jin-Kyu
Jeong, Kyu-Shik
Hong, Il-Hwa
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Several eradication programs have been developed and executed to curb alien invasive species that tend to damage the ecological environments they colonize; however, only few studies have evaluated the utilization of carcasses of these species after eradication.
Nutria (Myocastor coypus) is an invasive rodent species targeted by eradication programs in many countries.
We noted that nutria produce large amounts of ursodeoxycholic acid (UDCA) in their bile.
UDCA is a unique component responsible for the anti-inflammatory and hepatoprotective effects exerted by bear bile.
Therefore, we sought to examine the medicinal utility of nutria carcasses by investigating the hepatoprotective effect of their bile in mice.
C57BL/6 mice were injected with thioacetamide (TAA), which induced liver damage by increasing Kupffer cell infiltration.
Administration of nutria bile reduced hepatic inflammation, improved hepatic function, and increased the levels of senescence marker protein 30 (an indicator of hepatocyte viability).
Our results show that nutria bile exerts protective effects against TAA-induced liver injury in mice, suggesting that nutria carcasses may be used for the treatment of liver injuries.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kong, Joo-Yeon& Yeon, Seong-Chan& Lee, Hu Jang& Kang, Changkeun& Park, Jin-Kyu& Jeong, Kyu-Shik…[et al.]. 2019. Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150348
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kong, Joo-Yeon…[et al.]. Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1150348
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kong, Joo-Yeon& Yeon, Seong-Chan& Lee, Hu Jang& Kang, Changkeun& Park, Jin-Kyu& Jeong, Kyu-Shik…[et al.]. Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1150348
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1150348
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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