Meta-Analysis on the Efficacy and Safety of Traditional Chinese Medicine as Adjuvant Therapy for Refractory Androgenetic Alopecia
المؤلفون المشاركون
Ma, Xiao
You, Qiang
Li, Lan
Gao, Tian
Xiong, Suqin
Yan, Yufen
Fang, Hao
Li, Fengqing
Chen, Hongping
Liu, Youping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-21، 21ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-31
دولة النشر
مصر
عدد الصفحات
21
التخصصات الرئيسية
الملخص EN
Objective.
Traditional Chinese medicine (TCM) therapies have been widely used for the treatment of androgenetic alopecia (AGA) for thousands of years.
We conducted a meta-analysis to evaluate the curative efficacy and safety of TCM for treating AGA.
Methods.
Randomized controlled trials (RCTs) of TCM for the treatment of AGA through March 2019 were systematically identified in 4 English databases, namely, PubMed, Cochrane Library, EMBASE, and Web of Science, and 4 Chinese databases, namely, Sino-Med, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), and WanFang.
Quality assessment and data analysis were performed by Review Manager 5.3.5, and Stata 15.1 was used to cope with publication bias.
Results.
30 RCTs involving 2615 patients were randomly divided into a TCM group and a conventional medicine (CM) group.
The results showed that the total efficacy rate (TER) of the TCM group was significantly higher than that of the control group (OR = 3.34, 95% CI = 2.75–4.05, P<0.00001).
The total symptom score (TSS) of the TCM group was markedly reduced when compared with the CM group (SMD = −0.86; 95% CI = −1.19, −0.53; P<0.00001).
The microelement levels (Fe2+, Zn2+, and Cu2+) in hair were significantly improved when complemented with TCM therapy.
In addition, no significant differences were observed between the two groups in terms of adverse events (OR = 0.55, 95% CI = 0.29–1.05, P=0.07).
Conclusions.
In view of the effectiveness and safety of TCM, the present meta-analysis suggests that TCM could be recommended as an effective and safe adjuvant therapy for the treatment of AGA by improving the TER, symptoms, serum testosterone levels, and microelement levels.
However, long-term and higher-quality RCTs are needed to overcome the limitations of the selected studies and more precisely interrogate the efficacy and safety of TCM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
You, Qiang& Li, Lan& Ma, Xiao& Gao, Tian& Xiong, Suqin& Yan, Yufen…[et al.]. 2019. Meta-Analysis on the Efficacy and Safety of Traditional Chinese Medicine as Adjuvant Therapy for Refractory Androgenetic Alopecia. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-21.
https://search.emarefa.net/detail/BIM-1151645
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
You, Qiang…[et al.]. Meta-Analysis on the Efficacy and Safety of Traditional Chinese Medicine as Adjuvant Therapy for Refractory Androgenetic Alopecia. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-21.
https://search.emarefa.net/detail/BIM-1151645
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
You, Qiang& Li, Lan& Ma, Xiao& Gao, Tian& Xiong, Suqin& Yan, Yufen…[et al.]. Meta-Analysis on the Efficacy and Safety of Traditional Chinese Medicine as Adjuvant Therapy for Refractory Androgenetic Alopecia. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-21.
https://search.emarefa.net/detail/BIM-1151645
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151645
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر