Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide

الملخص EN

Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma.

Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection.

The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide.

Lenalidomide-associated allograft rejection has been reported in other organs.

However, this is the first case report of liver rejection induced by lenalidomide.