Comparison of Respiratory Pathogen Detection in Upper versus Lower Respiratory Tract Samples Using the BioFire FilmArray Respiratory Panel in the Immunocompromised Host
المؤلفون المشاركون
Limper, Andrew H.
Azadeh, Natalya
Sakata, Kenneth K.
Saeed, Ali
Mullon, John J.
Grys, Thomas E.
Binnicker, Matthew J.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The FilmArray Respiratory Panel (FARP) (BioFire Diagnostics, Inc.) is a multiplex, polymerase chain reaction (PCR) technique that can detect 17 respiratory viruses and 3 bacterial targets in a single reaction.
Immunocompromised hosts (ICH) with respiratory illnesses often undergo bronchoscopy with bronchoalveolar lavage (BAL).
This prospective study aimed to evaluate the yield and concordance of NP and BAL FARP testing when performed on the same patient concurrently.
Methods.
From February to December 2016, 125 patients (100 ICH and 25 non-ICH) were enrolled.
NP swabs and BAL samples were sent for FARP testing.
Results.
The yield of the BAL FARP among ICH and non-ICH was 24% (24/100) and 8% (2/25), respectively.
The yield of positive NP swabs in ICH was 27% (27/100) versus 4% (1/25) in non-ICH.
The majority of patients (89%; 111/125) had concordant results between NP and BAL specimens.
Of the 24 ICH patients who had a positive BAL FARP, the majority (79%) had the same pathogen detected from the NP swab.
Conclusion.
The FARP may be useful in the ICH.
Given the high concordance, in patients whom a pathogen is identified on the NP FARP, a FARP performed on BAL will likely yield the same result.
However, if the NP FARP is negative, performing the test on a BAL sample may have an incremental yield.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Azadeh, Natalya& Sakata, Kenneth K.& Saeed, Ali& Mullon, John J.& Grys, Thomas E.& Limper, Andrew H.…[et al.]. 2018. Comparison of Respiratory Pathogen Detection in Upper versus Lower Respiratory Tract Samples Using the BioFire FilmArray Respiratory Panel in the Immunocompromised Host. Canadian Respiratory Journal،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1151750
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Azadeh, Natalya…[et al.]. Comparison of Respiratory Pathogen Detection in Upper versus Lower Respiratory Tract Samples Using the BioFire FilmArray Respiratory Panel in the Immunocompromised Host. Canadian Respiratory Journal No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1151750
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Azadeh, Natalya& Sakata, Kenneth K.& Saeed, Ali& Mullon, John J.& Grys, Thomas E.& Limper, Andrew H.…[et al.]. Comparison of Respiratory Pathogen Detection in Upper versus Lower Respiratory Tract Samples Using the BioFire FilmArray Respiratory Panel in the Immunocompromised Host. Canadian Respiratory Journal. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1151750
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151750
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر