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LC-ESI-MSMS Phenolic Profile of Volutaria lippii (L.) Cass. Extracts and Evaluation of Their In Vitro Antioxidant, Antiacetylcholinesterase, Antidiabetic, and Antibacterial Activities
المؤلفون المشاركون
Smaoui, Slim
Ben Salah, Hichem
Allouche, Noureddine
Abdennabi, Raed
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-24
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Volutaria lippii (L.) Cass., an indigenous perennial herb from the Tunisian flora, belongs to the medicinally important genus Volutaria Cass.
(Asteraceae) which comprises eighteen species widely distributed in the Irano-Turanian and Mediterranean Basin.
In this study, five different extracts from Tunisian Volutaria lippii (L.) Cass.
were evaluated for their in vitro antioxidant, antiacetylcholinesterase, antidiabetic, and antibacterial activities as well as for their total phenolic and flavonoid contents.
The results indicated that the ethyl acetate and aqueous fractions have the highest levels in phenolic and flavonoid contents and showed remarkable antioxidant activities using DPPH (IC50= 11.50±0.57 and 28.81±1.35μg/mL, respectively), total antioxidant capacity (105.21±0.01 and 98.77±0.02 mg vitamin E/g extract, respectively), and reducing power (EC50= 55.40±2.00 and 66.65±1.40 μg/mL, respectively) methods.
Furthermore, they exhibited noticeable antiacetylcholinesterase and antidiabetic activities and a moderate antibacterial effect when compared to that of standards.
Principal component analysis allowed highlighting the ethyl acetate extract for its interesting acetylcholinesterase enzyme (AChE) and alpha-amylase activities and the aqueous fraction for its remarkably antibacterial activity, and their richness in phytochemical content.
Interestingly, the LC-ESI-MS/MS analyses of both fractions allowed the identification of ten phenolic acids and eight flavonoids.
The 3-O-caffeoylquinic and 3,4-di-O-caffeoylquinic acids constituted the most abundant components in the two fractions.
Taken together, these findings demonstrated, for the first time, that Volutaria lippii (L.) Cass.
is a potential source of biological active compounds which could be used in a wide range of fields, namely, nutrition and complementary pharmacological drug.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ben Salah, Hichem& Smaoui, Slim& Abdennabi, Raed& Allouche, Noureddine. 2019. LC-ESI-MSMS Phenolic Profile of Volutaria lippii (L.) Cass. Extracts and Evaluation of Their In Vitro Antioxidant, Antiacetylcholinesterase, Antidiabetic, and Antibacterial Activities. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1151941
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ben Salah, Hichem…[et al.]. LC-ESI-MSMS Phenolic Profile of Volutaria lippii (L.) Cass. Extracts and Evaluation of Their In Vitro Antioxidant, Antiacetylcholinesterase, Antidiabetic, and Antibacterial Activities. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1151941
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ben Salah, Hichem& Smaoui, Slim& Abdennabi, Raed& Allouche, Noureddine. LC-ESI-MSMS Phenolic Profile of Volutaria lippii (L.) Cass. Extracts and Evaluation of Their In Vitro Antioxidant, Antiacetylcholinesterase, Antidiabetic, and Antibacterial Activities. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1151941
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1151941
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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