Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population
المؤلفون المشاركون
Zhu, Li-Jin
Xia, Hai-Ling
Lou, Jian-Lin
Ying, Shibo
Yu, Min
Xiao, Yun
Jiang, Zhaoqiang
Shen, Wei
He, Xianglei
Chen, Junqiang
Feng, Lingfang
Ju, Li
Guo, Xinnian
Zhang, Yixiao
Shen, Jia-Wei
Tong, Yan
Zhang, Xing
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Fibulin-3 has been reported as a potential biomarker for mesothelioma.
However, little is known about the diagnostic efficacies of fibulin-3 for asbestos-related diseases (ARDs) in China.
This study was to investigate the utility of fibulin-3 for asbestos exposure and ARDs.
A total of 430 subjects were recruited from Southeast China, including healthy individuals, asbestos-exposed (AE) individuals, and patients with pleural plaques (PP), asbestosis, and malignant pleural mesothelioma (MPM).
Plasma fibulin-3 was measured using the enzyme-linked immunosorbent assay.
Linear regression analyses were applied to explore the influencing factors of fibulin-3.
Receiver operating characteristic curves were used to determine the cutoff values.
The median fibulin-3 level of subjects in the mesothelioma group was higher than that in other groups.
Subjects in the asbestosis group had higher median fibulin-3 level than those in the control group.
A higher fibulin-3 level was found in the group with ≥10 years of asbestos exposure as compared with control groups.
The AUCs of fibulin-3 for distinguishing MPM subjects from control, AE, PP, and asbestosis subjects were 0.92, 0.88, 0.90, and 0.81, respectively.
Our study provided evidence that fibulin-3 could be a potential biomarker for the early screening of MPM, but not of other nonmalignant ARDs in Chinese populations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jiang, Zhaoqiang& Ying, Shibo& Shen, Wei& He, Xianglei& Chen, Junqiang& Xia, Hai-Ling…[et al.]. 2017. Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population. Disease Markers،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1152203
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jiang, Zhaoqiang…[et al.]. Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population. Disease Markers No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1152203
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jiang, Zhaoqiang& Ying, Shibo& Shen, Wei& He, Xianglei& Chen, Junqiang& Xia, Hai-Ling…[et al.]. Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1152203
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152203
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر