Risk Factors Associated with Late Failure of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease
المؤلفون المشاركون
Han, Xiaoli
Chen, Tao
Bai, Linfu
Hu, Wenhui
Duan, Jun
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Risk factors for noninvasive ventilation (NIV) failure after initial success are not fully clear in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD).
Methods.
Patients who received NIV beyond 48 h due to acute exacerbation of COPD were enrolled.
However, we excluded those whose pH was higher than 7.35 or PaCO2 was less than 45 mmHg which was measured before NIV.
Late failure of NIV was defined as patients required intubation or died during NIV after initial success.
Results.
We enrolled 291 patients in this study.
Of them, 48 (16%) patients experienced late NIV failure (45 received intubation and 3 died during NIV).
The median time from initiation of NIV to intubation was 4.8 days (IQR: 3.4–8.1).
Compared with the data collected at initiation of NIV, the heart rate, respiratory rate, pH, and PaCO2 significantly improved after 1–2 h of NIV both in the NIV success and late failure of NIV groups.
Nosocomial pneumonia (odds ratio (OR) = 75, 95% confidence interval (CI): 11–537), heart rate at initiation of NIV (1.04, 1.01–1.06 beat per min), and pH at 1–2 h of NIV (2.06, 1.41–3.00 per decrease of 0.05 from 7.35) were independent risk factors for late failure of NIV.
In addition, the Glasgow coma scale (OR = 0.50, 95% CI: 0.34–0.73 per one unit increase) and PaO2/FiO2 (0.992, 0.986–0.998 per one unit increase) were independent protective factors for late failure of NIV.
In addition, patients with late failure of NIV had longer ICU stay (median 9.5 vs.
6.6 days) and higher hospital mortality (92% vs.
3%) compared with those with NIV success.
Conclusions.
Nosocomial pneumonia; heart rate at initiation of NIV; and consciousness, acidosis, and oxygenation at 1–2 h of NIV were associated with late failure of NIV in patients with COPD exacerbation.
And, late failure of NIV was associated with increased hospital mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Tao& Bai, Linfu& Hu, Wenhui& Han, Xiaoli& Duan, Jun. 2020. Risk Factors Associated with Late Failure of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease. Canadian Respiratory Journal،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1152231
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Tao…[et al.]. Risk Factors Associated with Late Failure of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease. Canadian Respiratory Journal No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1152231
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Tao& Bai, Linfu& Hu, Wenhui& Han, Xiaoli& Duan, Jun. Risk Factors Associated with Late Failure of Noninvasive Ventilation in Patients with Chronic Obstructive Pulmonary Disease. Canadian Respiratory Journal. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1152231
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152231
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر