Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children

الملخص EN

Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions.

PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease.

The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki diseases (KD) is still unclear.

In our study, we examined the PECAM-1 gene polymorphisms in 44 KD patients and 59 healthy children and revealed the correlation of PECAM-1 gene polymorphisms in KD children with and without coronary artery lesions (CAL).