Combination of Left Ventricular End-Diastolic Diameter and QRS Duration Strongly Predicts Good Response to and Prognosis of Cardiac Resynchronization Therapy
المؤلفون المشاركون
Wang, Jiang
Guo, Zhinian
Liu, Xiaoyan
Liu, Chuan
Cheng, Xiaofeng
Chen, Yunlong
Li, Ping
He, Yongming
Rao, Rongsheng
Li, Chun
Zhang, Yong
Luo, Xiaoyu
المصدر
Cardiology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-17
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Approximately 20–40% of recipients of cardiac resynchronization therapy (CRT) do not respond to it based on the current patient selection criteria.
The purpose of this study was to identify baseline parameters that can predict CRT response and to evaluate the effect of those predictive parameters on long-term prognosis.
Methods.
This was a retrospective, nonrandomized, noncontrolled cohort study.
Patients who received CRT in our centre were divided into responders and nonresponders by the definition of CRT response (an increase in left ventricular ejection fraction (LVEF) of ≥5% and improvement of ≥1 New York Heart Association (NYHA) class from baseline to the 6-month follow-up).
Results.
Of the 101 patients, 68 were responders and 33 were nonresponders.
Left ventricular end-diastolic diameter (LVEDD; OR: 0.88, 95% CI: 0.81–0.95, P=0.001) and QRS duration (OR: 1.07, 95% CI: 1.04–1.10, P<0.001) were independent predictors of CRT response.
The combination of LVEDD and QRS duration was more valuable for predicting CRT response (AUC 0.836; 95% CI: 0.76–0.91; P<0.001).
Moreover, the combination of LVEDD ≤ 71 mm and QRS duration ≥ 170 ms had a low incidence of all-cause mortality, HF hospitalisation, and the composite endpoint.
In addition, baseline LVEDD had a positive correlation with QRS duration (R=0.199, P=0.046).
Responders to CRT had better LV reverse remodeling.
Conclusion.
The combination of LVEDD and QRS duration provided more robust prediction of CRT response.
Moreover, the combination of LVEDD ≤ 71 mm and QRS duration ≥ 170 ms was associated with a low incidence of all-cause mortality, HF hospitalisation, and the composite endpoint.
Our results may be useful to provide individualized patient selection for CRT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Zhinian& Liu, Xiaoyan& Cheng, Xiaofeng& Liu, Chuan& Li, Ping& He, Yongming…[et al.]. 2020. Combination of Left Ventricular End-Diastolic Diameter and QRS Duration Strongly Predicts Good Response to and Prognosis of Cardiac Resynchronization Therapy. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152308
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Zhinian…[et al.]. Combination of Left Ventricular End-Diastolic Diameter and QRS Duration Strongly Predicts Good Response to and Prognosis of Cardiac Resynchronization Therapy. Cardiology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1152308
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Zhinian& Liu, Xiaoyan& Cheng, Xiaofeng& Liu, Chuan& Li, Ping& He, Yongming…[et al.]. Combination of Left Ventricular End-Diastolic Diameter and QRS Duration Strongly Predicts Good Response to and Prognosis of Cardiac Resynchronization Therapy. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1152308
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152308
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر