Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity
المؤلفون المشاركون
Campos Junior, Mário
Fonseca, Ana Carolina Proença da
Ochioni, Alan Cleveland
Martins, Raisa da Silva
Zembrzuski, Verônica Marques
Ramos, Vivianne Galante
Carneiro, João Regis Ivar
Cabello, Pedro Hernan
Cabello, Giselda Maria Kalil
Nogueira Neto, José Firmino
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Obesity is the most common nutritional disorder.
This disease is a multifactorial disease influenced by environmental and genetic factors.
This study investigated the relationship between common variants of adiponectin (ADIPOQ), retinoic acid receptor responder 2 (RARRES2), and peroxisome proliferator-activated receptor-γ coativator-1 (PPARGC1) and obesity-related traits and susceptibility.
A total of 167 individuals with obesity and 165 normal-weight subjects were recruited.
Genotype frequencies of rs182052 in ADIPOQ differed significantly between the groups.
Genotype AA was observed at a higher frequency in case than in control subjects.
Association analysis showed that the A allele was a risk factor for obesity.
This polymorphism was associated with body weight, body mass index (BMI), and waist circumference.
After stratification by BMI, eutrophic individuals with AA or AG genotypes had higher body weights and waist circumferences than those with GG genotypes.
In the case group, no associations were observed, except for stratified subjects with morbid obesity that exhibited a progressive increase of body weight, BMI, and waist circumference when rs182052 A was present.
No associations were observed between SNPs in RARRES2 and PPARGC1 and obesity or any other studied variables.
The rs182052 polymorphism in ADIPOQ is associated with a higher risk for obesity and obesity-related parameters.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fonseca, Ana Carolina Proença da& Ochioni, Alan Cleveland& Martins, Raisa da Silva& Zembrzuski, Verônica Marques& Campos Junior, Mário& Ramos, Vivianne Galante…[et al.]. 2017. Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity. Disease Markers،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1152379
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fonseca, Ana Carolina Proença da…[et al.]. Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity. Disease Markers No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1152379
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fonseca, Ana Carolina Proença da& Ochioni, Alan Cleveland& Martins, Raisa da Silva& Zembrzuski, Verônica Marques& Campos Junior, Mário& Ramos, Vivianne Galante…[et al.]. Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1152379
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152379
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر