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Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome
المؤلفون المشاركون
Kang, Seung-Ji
Kim, Uh Jin
Oh, Tae hoon
Kim, Bansuk
Kim, Seong Eun
Park, Kyung-Hwa
Jung, Sook-In
Jang, Hee-Chang
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral disease in East Asia with high mortality.
Few studies have examined markers that suggest SFTS in febrile patients.
To determine useful biochemical markers for SFTS, patients aged 18 years or older with SFTS or microbiologically confirmed community-onset bacteremia with thrombocytopenia (BT) at presentation between June 2013 and December 2015 were included from two tertiary university hospitals in Republic of Korea retrospectively.
Eleven patients with SFTS and 62 patients with bacteremia and thrombocytopenia were identified in the study period.
Age and sex did not show significant difference among two groups.
Fever was more commonly observed but comorbidities were less common in SFTS than in BT (P<0.05, each).
The areas under the curves of serum ferritin, C-reactive protein, white blood cell count, serum procalcitonin, and fibrinogen were above 0.9, indicating the discriminative power of these biomarkers (1.000, 0.991, 0.963, 0.931, and 0.934, resp., all P<0.05).
The optimal cutoff value of serum ferritin was 3,822 ng/mL in this study.
These results suggest that hyperferritinemia is a typical laboratory feature of SFTS, and the serum ferritin level can be used as a marker for clinicians suspecting SFTS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Uh Jin& Oh, Tae hoon& Kim, Bansuk& Kim, Seong Eun& Kang, Seung-Ji& Park, Kyung-Hwa…[et al.]. 2017. Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome. Disease Markers،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152447
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Uh Jin…[et al.]. Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome. Disease Markers No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1152447
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Uh Jin& Oh, Tae hoon& Kim, Bansuk& Kim, Seong Eun& Kang, Seung-Ji& Park, Kyung-Hwa…[et al.]. Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome. Disease Markers. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1152447
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152447
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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