Balloon Deflation Strategy during Primary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Clinical Trial and Numerical Simulation-Based Analysis
المؤلفون المشاركون
Wang, Xiao-fei
Chen, Kan
He, Qing
Fan, Li
Zhuo, Yang
Gu, Jun
Liu, Tian-jiao
Yin, Zhao-fang
Xu, Zuo-jun
Zeng, Hua-su
Fan, Yu-qi
Zhang, Jun-feng
Liang, Fu-you
Wang, Chang-qian
Li, Jie
المصدر
Cardiology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Primary percutaneous coronary intervention (PCI) is the best available reperfusion strategy in patients with acute ST-segment elevation myocardial infarction (STEMI).
However, PCI is associated with a serious problem known as no-reflow phenomenon, resulting in poor clinical and functional outcomes.
This study aimed to compare the influences of different balloon deflation velocity on coronary flow and cardiovascular events during primary PCI in STEM as well as transient hemodynamic changes in in vitro experiments.
Method and Results.
211 STEMI patients were randomly assigned to either a rapid or a slow balloon deflation group during stent deployment.
The primary end point was coronary flow at the end of PCI procedure, and secondary end points included myocardial infarct size.
Transient hemodynamic changes were evaluated through an in vitro experimental apparatus and a computer model.
In clinical practice, the level of corrected TIMI frame count (cTFC) in slow balloon deflation after primary PCI was significantly lower than that of rapid balloon deflation, which was associated with smaller infarct size.
Numerical simulations revealed that the rapid deflation led to a sharp acceleration of flow in the balloon-vessel gap and a concomitant abnormal rise in wall shear stress (WSS).
Conclusion.
This randomized study demonstrated that the slow balloon deflation during stent implantation improved coronary flow and reduced infarct size in reperfused STEMI.
The change of flow in the balloon-vessel gap and WSS resulted from different balloon deflation velocity might be partly accounted for this results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gu, Jun& Zhuo, Yang& Liu, Tian-jiao& Li, Jie& Yin, Zhao-fang& Xu, Zuo-jun…[et al.]. 2020. Balloon Deflation Strategy during Primary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Clinical Trial and Numerical Simulation-Based Analysis. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1152467
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gu, Jun…[et al.]. Balloon Deflation Strategy during Primary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Clinical Trial and Numerical Simulation-Based Analysis. Cardiology Research and Practice No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1152467
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gu, Jun& Zhuo, Yang& Liu, Tian-jiao& Li, Jie& Yin, Zhao-fang& Xu, Zuo-jun…[et al.]. Balloon Deflation Strategy during Primary Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Clinical Trial and Numerical Simulation-Based Analysis. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1152467
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152467
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر