Managing Nonagenarians with Acute Myocardial Infarction: Invasive versus Conservative Treatment
المؤلفون المشاركون
Lim, Hong-Seok
Lee, Jooho
Seo, Kyoung-Woo
Park, Jin-Sun
Yang, Hyoung-Mo
Choi, Byoung-Joo
Choi, So-Yeon
Yoon, Myeong-Ho
Hwang, Gyo-Seung
Tahk, Seung-Jae
Shin, Joon-Han
المصدر
Cardiology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Limited data are available to support an invasive treatment strategy in nonagenarians with acute myocardial infarction (AMI).
We aimed to investigate whether percutaneous coronary intervention (PCI) is beneficial in this frail population.
Methods.
We retrospectively analyzed 41 nonagenarians with AMI (both ST-segment-elevation and non-ST-segment-elevation MI) between 2006 and 2015 in a single center.
We assessed 30-day and one-year mortality rates according to the treatment strategy.
Results.
Among study subjects, 24 (59%) were treated with PCI (PCI group) and 17 (41%) were treated with conservative management (medical treatment group) per the clinician’s discretion.
The median follow-up duration was 30 months (0–74 months).
Thirty-day mortality was lower in the PCI group than in the medical treatment group (17% vs.
65%; P<0.001).
One-year mortality was also lower in the PCI group than in the medical treatment group (21% vs.
76%; P<0.001).
The PCI group presented a 73% decreased risk of death (adjusted hazard ratio: 0.269; 95% confidence interval: 0.126–0.571; P<0.001).
In the Killip class 1 through 3 subgroups (n = 36), 30-day and one-year mortality were still higher among those in the medical treatment group (13% vs.
54% at 30 days; P<0.001 and 17% vs.
69% at one year; P<0.001).
Landmark analysis after 30 days revealed no significant difference in the cumulative mortality rate between the two groups, indicating that the mortality difference was mainly determined within the first 30 days after AMI.
Conclusion.
Mortality after AMI was decreased in correlation with the invasive strategy relative to the conservative strategy, even in nonagenarians.
Regardless of age, PCI should be considered in AMI patients.
However, large-scale randomized controlled trials are needed to support our conclusion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Jooho& Seo, Kyoung-Woo& Park, Jin-Sun& Yang, Hyoung-Mo& Lim, Hong-Seok& Choi, Byoung-Joo…[et al.]. 2020. Managing Nonagenarians with Acute Myocardial Infarction: Invasive versus Conservative Treatment. Cardiology Research and Practice،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152623
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Jooho…[et al.]. Managing Nonagenarians with Acute Myocardial Infarction: Invasive versus Conservative Treatment. Cardiology Research and Practice No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1152623
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Jooho& Seo, Kyoung-Woo& Park, Jin-Sun& Yang, Hyoung-Mo& Lim, Hong-Seok& Choi, Byoung-Joo…[et al.]. Managing Nonagenarians with Acute Myocardial Infarction: Invasive versus Conservative Treatment. Cardiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1152623
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152623
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر