The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction
المؤلفون المشاركون
Peixoto Sobrinho, Tadeu José da Silva
Pupo, André Sampaio
Nunes-Neto, Paulo Alexandre
da Silva Júnior, Edilson Dantas
Leopoldina da Silva, Jamilka
Rodrigo da Silva Oliveira, Alisson
Costa-Silva, João Henrique da
Wanderley, Almir Gonçalves
Araújo, Alice Valença
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-27
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Schinus terebinthifolius Raddi (Anacardiaceae), popularly known as red aroeira, is used in traditional medicine to treat inflammatory, gastric, and respiratory disorders.
The aim of this study was to evaluate the antihistaminic activity of S.
terebinthifolius (St) bark extract by using in vivo and in vitro experimental models.
The effects of St were investigated on contractions induced by histamine, carbachol, and potassium chloride in isolated guinea pig ileum.
St was also studied in response to hind paw edema induced by histamine in rats.
Experiments revealed that although St (250, 500, and 1,000 µg/mL) reduced the histamine-induced contractions by 9.1±1.8, 50.2±2.0, and 68.9±2.0%, respectively, it did not inhibit contractions induced by carbachol or KCl.
The association of St (250 and 500 µg/mL) with hydroxyzine, an H1-antihistamine (0.125 and 0.250 µM), increased the inhibitory effect to 67.0±3.2 and 85.1±2.1%, respectively.
Moreover, St (100, 200, and 400 mg/kg) decreased paw edema from its peak by 33.9, 48.4, and 54.8%, respectively, whereas hydroxyzine (70 mg/kg) inhibited the peak edema by 56.5%.
Altogether, the results suggest that the bark extract of S.
terebinthifolius has an antihistaminic effect (H1).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nunes-Neto, Paulo Alexandre& Peixoto Sobrinho, Tadeu José da Silva& da Silva Júnior, Edilson Dantas& Leopoldina da Silva, Jamilka& Rodrigo da Silva Oliveira, Alisson& Pupo, André Sampaio…[et al.]. 2017. The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1152992
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nunes-Neto, Paulo Alexandre…[et al.]. The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1152992
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nunes-Neto, Paulo Alexandre& Peixoto Sobrinho, Tadeu José da Silva& da Silva Júnior, Edilson Dantas& Leopoldina da Silva, Jamilka& Rodrigo da Silva Oliveira, Alisson& Pupo, André Sampaio…[et al.]. The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1152992
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1152992
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر