Antidepressant-Like Effect of Lipid Extract of Channa striatus in Postpartum Model of Depression in Rats
المؤلفون المشاركون
Basir, Rusliza
Abdul Shukkoor, Mohamed Saleem
Baharuldin, Mohamad Taufik Hidayat Bin
Mat Jais, Abdul Manan
Mohamad Moklas, Mohamad Aris
Fakurazi, Sharida
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-29
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Postpartum depression affects 15% of women.
Channa striatus, a freshwater fish, is consumed in local Malay population as a rejuvenating diet during postpartum period.
This study evaluated the antidepressant-like effect of lipid extract of C.
striatus fillet and its mechanism of action in female Sprague-Dawley rats in postpartum model of depression.
The rats were ovariectomized and treated with high dose of progesterone and estradiol benzoate for 23 days to have hormone-simulated pregnancy.
The day 24 and afterwards were considered as the postpartum period.
During the postpartum period, lipid extract was administered at 125, 250, and 500 mg/kg through intraperitoneal route for 15 days.
Fluoxetine (10 mg/kg) was used as the positive control.
On postpartum day 15, the animals were tested in forced swimming test (FST) and open field test (OFT) followed by biochemical analysis.
Withdrawal of hormone administration during the postpartum period induced depressive-like behavior in FST.
Administration of lipid extract reversed that depressive-like behavior at 125, 250, and 500 mg/kg in FST.
In OFT, it decreased the exploratory activity.
The mechanism of the antidepressant-like effect may be mediated through the decrease in plasma corticosterone, increase in plasma oxytocin, and decrease in nuclear factor-kappa B in prefrontal cortex of rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdul Shukkoor, Mohamed Saleem& Baharuldin, Mohamad Taufik Hidayat Bin& Mat Jais, Abdul Manan& Mohamad Moklas, Mohamad Aris& Fakurazi, Sharida& Basir, Rusliza. 2017. Antidepressant-Like Effect of Lipid Extract of Channa striatus in Postpartum Model of Depression in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1153001
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdul Shukkoor, Mohamed Saleem…[et al.]. Antidepressant-Like Effect of Lipid Extract of Channa striatus in Postpartum Model of Depression in Rats. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1153001
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdul Shukkoor, Mohamed Saleem& Baharuldin, Mohamad Taufik Hidayat Bin& Mat Jais, Abdul Manan& Mohamad Moklas, Mohamad Aris& Fakurazi, Sharida& Basir, Rusliza. Antidepressant-Like Effect of Lipid Extract of Channa striatus in Postpartum Model of Depression in Rats. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1153001
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153001
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر