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Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients
المؤلفون المشاركون
Çelik, Sebahattin
Sayir, Fuat
Mergan, Duygu
Dülger, Ahmet Cumhur
Kemik, Özgür
Cobanoglu, Ufuk
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-17
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Objective.
Elevated serum Mac 2-binding protein (M2BP) levels have been observed in some cancers.
As far as we know, its importance has not been investigated in esophageal squamous cell carcinoma (ESCC).
The investigated problem of this study was to evaluate whether there was a difference between ESCC patients and the control group in terms of M2BP.
Also, we evaluated the diagnostic performance of serum M2BP alone or in combination with the CEA for patients with ESCC.
Material and Methods.
Blood serum samples were collected from 50 healthy donors and 150 patients with ESCC.
M2BP levels of all 200 samples were quantified by ELISA (enzyme-linked immunosorbent assay).
Patients who had been diagnosed with ESCC and did not have any other malignancies were enrolled to study.
Results.
The two groups did not significantly differ in terms of age (p>0.05).
In the control group, the mean serum M2BP level was 14.97 ± 3.46 ng/mL.
The mean serum M2BP level of the ESCC patients was 176.65 ± 22.14 ng/mL.
The serum M2BP level was significantly higher in patients with ESCC than in the control group (p<0.001).
Gender was also comparable in both groups (p=0.695).
Conclusions.
Our analysis demonstrated that this marker may be associated with the mechanism of the disease.
Despite that serum M2BP is not a specific marker for ESCC, it can be used as an adjuvant biomarker for the diagnosis of ESCC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cobanoglu, Ufuk& Mergan, Duygu& Dülger, Ahmet Cumhur& Çelik, Sebahattin& Kemik, Özgür& Sayir, Fuat. 2018. Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients. Disease Markers،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1153251
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cobanoglu, Ufuk…[et al.]. Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients. Disease Markers No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1153251
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cobanoglu, Ufuk& Mergan, Duygu& Dülger, Ahmet Cumhur& Çelik, Sebahattin& Kemik, Özgür& Sayir, Fuat. Are Serum Mac 2-Binding Protein Levels Elevated in Esophageal Cancer? A Control Study of Esophageal Squamous Cell Carcinoma Patients. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1153251
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153251
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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