Correlation of Triiodothyronine Level with In-Hospital Cardiac Function and Long-Term Prognosis in Patients with Acute Myocardial Infarction
المؤلفون المشاركون
Sun, Lizhe
Xia, Yu-Long
She, Jianqing
Feng, Jiahao
Deng, Yangyang
Wu, Yue
Guo, Manyun
Liang, Xiao
Li, Jingjin
Yuan, Zuyi
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
The pathophysiologic mechanism of how thyroid function is related to the development and prognosis of acute myocardial infarction (AMI) remains under explored, and there has been a lack of clinical investigations.
In this study, we investigate the relationship between triiodothyronine (T3) level and cardiac ejection fraction (EF) as well as probrain natriuretic peptide (NT-proBNP) on admission and subsequent prognosis in AMI patients.
Methods.
We measured admission thyroid function, NT-proBNP, and EF by echocardiography in 345 patients diagnosed with AMI.
Simple and multiregression analyses were performed to investigate the correlation between T3 level and EF as well as NT-proBNP.
Major adverse cardiovascular events (MACE), including new-onset myocardial infarction, acute heart failure, and cardiac death, were documented during the follow-up.
248 participants were separated into three groups based on T3 and free triiodothyronine (FT3) levels for survival analysis during a 2-year follow-up.
Results.
345 patients diagnosed with AMI were included in the initial observational analysis.
248 AMI patients were included in the follow-up survival analysis.
The T3 levels were found to be significantly positively correlated with EF (R square=0.042, P<0.001) and negatively correlated with admission NT-proBNP levels (R square=0.059, P<0.001), which is the same with the correlation between FT3 and EF (R square=0.053, P<0.001) and admission NT-proBNP levels (R square=0.108, P<0.001).
Kaplan-Meier survival analysis revealed no significant difference with regard to different T3 or FT3 levels at the end of follow-up.
Conclusions.
T3 and FT3 levels are moderately positively correlated with cardiac function on admission in AMI patients but did not predict a long-time survival rate.
Further studies are needed to explain whether longer-term follow-up would further identify the prognosis effect of T3 on MACE and all-cause mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
She, Jianqing& Feng, Jiahao& Deng, Yangyang& Sun, Lizhe& Wu, Yue& Guo, Manyun…[et al.]. 2018. Correlation of Triiodothyronine Level with In-Hospital Cardiac Function and Long-Term Prognosis in Patients with Acute Myocardial Infarction. Disease Markers،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153419
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
She, Jianqing…[et al.]. Correlation of Triiodothyronine Level with In-Hospital Cardiac Function and Long-Term Prognosis in Patients with Acute Myocardial Infarction. Disease Markers No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1153419
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
She, Jianqing& Feng, Jiahao& Deng, Yangyang& Sun, Lizhe& Wu, Yue& Guo, Manyun…[et al.]. Correlation of Triiodothyronine Level with In-Hospital Cardiac Function and Long-Term Prognosis in Patients with Acute Myocardial Infarction. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153419
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153419
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر