Roles of Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide in Predicting Catheter-Related Bloodstream Infection in Severe Burn Injury Patients
المؤلفون المشاركون
Zhou, Bao-Chun
Zhu, Jian-Jun
Liu, Li-Jun
Mao, Ziruo
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-22
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the characteristics of early catheter-related bloodstream infection (CRBSI) in severe burn injury patients induced by a massive aluminum dust explosion.
Methods.
Sixty-eight severe burn injury patients experienced a massive dust explosion in Kunshan were included in this study.
Patients received central venous catheter placement, arterial catheterization to monitor blood pressure and PiCCO cardiac monitoring, tracheostomy, mechanical ventilation, analgesics and sedation treatment, and fluid resuscitation.
Clinical data including age, gender, burn surface area, fluid intake and output, urine temperature, and APACHE II score information were collected from each patient.
Ultrasound screening was performed to exclude heart failure, which may lead to the change of NT-proBNP.
When CRBSI was suspected, 10 ml central venous blood and peripheral arterial blood were sent for testing.
For patients with suspected CRBSI, the level of PCT and NT-proBNP were monitored every day until the infection was controlled.
Results.
Among the 68 patients, 29 showed CRBSI.
The most common pathogenic bacteria of CRBSI were A.
baumannii (39.8%), P.
aeruginosa (26.4%), and K.
pneumoniae (13.7%).
Procalcitonin (PCT) (2.98 ng/ml) and NT-proBNP (355 pg/ml) were significantly associated with CRBSI results.
The sensitivity of PCT, NT-proBNP, WBC, and CRP was 94.2%, 89.7%, 88.3%, and 90.5%, respectively (P<0.05).
The area under curve (AUC) of PCT combined with NT-proBNP for prediction of CRBSI was 0.981, and the sensitivity and specificity was 0.812 and 0.857, respectively.
Conclusion.
PCT and NT-proBNP combination improves the diagnosis of CRBSI.
PCT and NT-proBNP may be alternative candidates for potential prediction of CRBSI in patients with severe injury.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Bao-Chun& Zhu, Jian-Jun& Mao, Ziruo& Liu, Li-Jun. 2018. Roles of Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide in Predicting Catheter-Related Bloodstream Infection in Severe Burn Injury Patients. Disease Markers،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1153442
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Bao-Chun…[et al.]. Roles of Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide in Predicting Catheter-Related Bloodstream Infection in Severe Burn Injury Patients. Disease Markers No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1153442
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Bao-Chun& Zhu, Jian-Jun& Mao, Ziruo& Liu, Li-Jun. Roles of Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide in Predicting Catheter-Related Bloodstream Infection in Severe Burn Injury Patients. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1153442
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153442
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر