Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms
المؤلفون المشاركون
Habtemariam, Solomon
Elufioye, Taiwo Olayemi
Berida, Tomayo Ireti
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-27، 27ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-22
دولة النشر
مصر
عدد الصفحات
27
التخصصات الرئيسية
الملخص EN
Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs).
The various NDs including Alzheimer’s, Parkinson’s, and Huntington’s diseases as well as amyotropic lateral sclerosis affect millions of people around the world with the main risk factor being advancing age.
Each of these diseases affects specific neurons and/or regions in the brain and involves characteristic pathological and molecular features.
Hence, several in vitro and in vivo study models specific to each disease have been employed to study NDs with the aim of understanding their underlying mechanisms and identifying new therapeutic strategies.
Of the most prevalent drug development efforts employed in the past few decades, mechanisms implicated in the accumulation of protein-based deposits, oxidative stress, neuroinflammation, and certain neurotransmitter deficits such as acetylcholine and dopamine have been scrutinized in great detail.
In this review, we presented classical examples of plant-derived neuroprotective agents by highlighting their structural class and specific mechanisms of action.
Many of these natural products that have shown therapeutic efficacies appear to be working through the above-mentioned key multiple mechanisms of action.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Elufioye, Taiwo Olayemi& Berida, Tomayo Ireti& Habtemariam, Solomon. 2017. Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1153537
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Elufioye, Taiwo Olayemi…[et al.]. Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-27.
https://search.emarefa.net/detail/BIM-1153537
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Elufioye, Taiwo Olayemi& Berida, Tomayo Ireti& Habtemariam, Solomon. Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1153537
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153537
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر