![](/images/graphics-bg.png)
The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis
المؤلف
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Intrauterine sex hormone environment as indicated by the second to the fourth digit ratio (2D : 4D) can be associated with cancer risk.
This systematic review and meta-analysis aimed to evaluate the association of 2D : 4D with cancer diagnosis, malignancy, and age at presentation.
Methods.
Studies that evaluated the association of 2D : 4D with cancer risk were collected from Pubmed/MEDLINE and Clarivate Analytics databases.
Nineteen studies were included in the qualitative analysis.
Results.
The 2D : 4D ratio was studied in prostate cancer, breast cancer, testicular cancer, gastric cancer, oral cancer, brain tumors, and cervical intraepithelial neoplasia.
Low 2D : 4D was associated with prostate cancer, gastric cancer, and brain tumors, while high 2D : 4D, with breast cancer risk and cervical dysplasia.
The 2D : 4D ratio was not associated with prostate, breast, and gastric cancer stage.
Greater 2D : 4D ratio was associated with younger presentation of breast cancer and brain tumors.
The meta-analyses demonstrated that testicular cancer was not associated with right-hand 2D : 4D ratio (p=0.74) and gastric cancer was not associated with right-hand (p=0.15) and left-hand (p=0.95) 2D : 4D ratio.
Conclusions.
Sex hormone environment during early development is associated with cancer risk later in life.
Further studies exploring the link between intrauterine hormone environment and cancer risk are encouraged.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bunevicius, Adomas. 2018. The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis. Disease Markers،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153660
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bunevicius, Adomas. The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis. Disease Markers No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1153660
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bunevicius, Adomas. The Association of Digit Ratio (2D : 4D) with Cancer: A Systematic Review and Meta-Analysis. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1153660
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153660
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)