The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial
المؤلفون المشاركون
Leiva, E.
Mujica, V.
Orrego, R.
Zúñiga-Hernández, Jessica
Pérez, Jorge
Romero, Paula
Ovalle, Paz
Arredondo, Miguel
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-30
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Although there is evidence of the benefits of propolis on human health, the vast majority of studies have been conducted using animal models.
The present study includes the chemical characterization and clinical evaluation of the effects of the oral administration of propolis solution on the oxidative status and modulation of lipids in a human population in Talca, Chile.
Chemical characterization of propolis, total phenol, flavonoids, and total antioxidant capacity were determined by ORAC.
Identification of phenols and flavonoids in propolis was assessed by HPLC-DAD.
A double-blind, placebo-controlled clinical trial was conducted.
Subjects provided informed consent form and the Bioethics Committee of the Universidad de Talca approved protocol.
Eligible subjects (n=67) were randomized in two groups: propolis (n=35) and placebo (n=32).
All subjects were evaluated at 0 (baseline), 45, and 90 days.
In the propolis group, we observed that increases in HDL-c went from 53.9 ± 11.9 to 65.8 ± 16.7 mg/dL (p<0.001) from baseline to 90 days.
Compared to placebo subjects, consumption of propolis induced a net increase in GSH levels (p<0.0001) and a decrease (p<0.001) in TBARS levels for the propolis group.
Our findings indicate potential benefits of propolis use in human health.
The use of propolis appears to have positive effects on oxidative status and improvement of HDL-c, both of which contribute to a reduced risk of cardiovascular disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mujica, V.& Orrego, R.& Pérez, Jorge& Romero, Paula& Ovalle, Paz& Zúñiga-Hernández, Jessica…[et al.]. 2017. The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1153705
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mujica, V.…[et al.]. The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1153705
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mujica, V.& Orrego, R.& Pérez, Jorge& Romero, Paula& Ovalle, Paz& Zúñiga-Hernández, Jessica…[et al.]. The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1153705
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153705
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر