Phylogenetic Tree Analysis of the Cold-Hot Nature of Traditional Chinese Marine Medicine for Possible Anticancer Activity

المؤلفون المشاركون

Fu, Xianjun
Wang, Zhenguo
Song, Xuxia
Li, Xuebo
Wong, Kah Keng
Li, Jiaoyang
Zhang, Fengcong
Wang, Changyun

المصدر

Evidence-Based Complementary and Alternative Medicine

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-01-12

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الطب البشري

الملخص EN

Traditional Chinese Marine Medicine (TCMM) represents one of the medicinal resources for research and development of novel anticancer drugs.

In this study, to investigate the presence of anticancer activity (AA) displayed by cold or hot nature of TCMM, we analyzed the association relationship and the distribution regularity of TCMMs with different nature (613 TCMMs originated from 1,091 species of marine organisms) via association rules mining and phylogenetic tree analysis.

The screened association rules were collected from three taxonomy groups: (1) Bacteria superkingdom, Phaeophyceae class, Fucales order, Sargassaceae family, and Sargassum genus; (2) Viridiplantae kingdom, Streptophyta phylum, Malpighiales class, and Rhizophoraceae family; (3) Holothuroidea class, Aspidochirotida order, and Holothuria genus.

Our analyses showed that TCMMs with closer taxonomic relationship were more likely to possess anticancer bioactivity.

We found that the cluster pattern of marine organisms with reported AA tended to cluster with cold nature TCMMs.

Moreover, TCMMs with salty-cold nature demonstrated properties for softening hard mass and removing stasis to treat cancers, and species within Metazoa or Viridiplantae kingdom of cold nature were more likely to contain AA properties.

We propose that TCMMs from these marine groups may enable focused bioprospecting for discovery of novel anticancer drugs derived from marine bioresources.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Fu, Xianjun& Song, Xuxia& Li, Xuebo& Wong, Kah Keng& Li, Jiaoyang& Zhang, Fengcong…[et al.]. 2017. Phylogenetic Tree Analysis of the Cold-Hot Nature of Traditional Chinese Marine Medicine for Possible Anticancer Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153731

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Fu, Xianjun…[et al.]. Phylogenetic Tree Analysis of the Cold-Hot Nature of Traditional Chinese Marine Medicine for Possible Anticancer Activity. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153731

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Fu, Xianjun& Song, Xuxia& Li, Xuebo& Wong, Kah Keng& Li, Jiaoyang& Zhang, Fengcong…[et al.]. Phylogenetic Tree Analysis of the Cold-Hot Nature of Traditional Chinese Marine Medicine for Possible Anticancer Activity. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153731

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1153731