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Platelet Distribution Width at First Day of Hospital Admission in Patients with Hemorrhagic Fever with Renal Syndrome Caused by Hantaan Virus May Predict Disease Severity and Critical Patients’ Survival
المؤلفون المشاركون
Li, Na
Fan, Xiude
Han, Qunying
Liu, Zhengwen
Liu, Zitong
Fu, Shiqi
Sang, Jiao
Deng, Huan
Li, Fang
Zhang, Xiaoge
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Thrombocytopenia is one of the main characteristics of hemorrhagic fever with renal syndrome (HFRS).
This study aimed to evaluate the associations of platelet distribution width (PDW) with the disease severity and critical patients’ survival of HFRS.
The demographics, clinical data, and white blood cell and platelet parameters including PDW in 260 patients hospitalized for HFRS were analyzed.
The results showed that PDW on the first day (PDW1) was positively associated with the disease severity (p=0.005).
Multiple regression analysis showed that in addition to age (odds ratio [OR], 1.091; 95% confidence interval [CI], 1.015–1.172) and occurrence of sepsis (OR, 22.283; 95% CI, 2.985–166.325), PDW1 (OR, 0.782; 95% CI, 0.617–0.992) was a risk factor of the mortality, having an area under the receiver operating characteristic curve of 0.709 (95% CI, 0.572–0.846, p=0.013) for predicting mortality, with a sensitivity of 70% and a specificity of 67% at a cutoff of 16.5 fL, in patients with critical HFRS.
These results suggest the potential of PDW at the first day of hospitalization as a valuable parameter for evaluating the severity of HFRS and a moderate parameter for predicting the prognosis of critical HFRS patients.
A prospective study in large patient population is needed to validate these findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fan, Xiude& Liu, Zitong& Fu, Shiqi& Sang, Jiao& Deng, Huan& Li, Fang…[et al.]. 2018. Platelet Distribution Width at First Day of Hospital Admission in Patients with Hemorrhagic Fever with Renal Syndrome Caused by Hantaan Virus May Predict Disease Severity and Critical Patients’ Survival. Disease Markers،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153784
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fan, Xiude…[et al.]. Platelet Distribution Width at First Day of Hospital Admission in Patients with Hemorrhagic Fever with Renal Syndrome Caused by Hantaan Virus May Predict Disease Severity and Critical Patients’ Survival. Disease Markers No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1153784
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fan, Xiude& Liu, Zitong& Fu, Shiqi& Sang, Jiao& Deng, Huan& Li, Fang…[et al.]. Platelet Distribution Width at First Day of Hospital Admission in Patients with Hemorrhagic Fever with Renal Syndrome Caused by Hantaan Virus May Predict Disease Severity and Critical Patients’ Survival. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153784
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153784
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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