Pentraxin 3 (PTX-3) Levels in Bronchoalveolar Lavage Fluid as a Lung Cancer Biomarker
المؤلفون المشاركون
Chammout, Anwar
Ghabally, Mike
Masri, Christina
Tantak, Nour
Ward, Fadi
Omar, Ghefar
Gennatas, Constantine
Chen, Xue
Shen, Liangrong
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
In this study, we investigated the utility of pentraxin 3 (PTX-3) in bronchoalveolar lavage fluid (BALF) as lung cancer (LCa) diagnostic.
A total of 89 LCa patients and 84 non-LCa patients who received bronchoscopy in the First Affiliated Hospital of Xi’an Jiaotong University from December 2014 to February 2015 were enrolled.
LCa was subdivided according to pathological type (scale, gland, and small cell lung cancer).
BALF samples were obtained during bronchoscopy and PTX-3 levels assayed by ELISA.
t-tests, Mann-Whitney, and Kruskal-Wallis tests were performed for the comparison of PTX-3 levels between the different groups.
Correlation analysis and receiver operating characteristic (ROC) analysis were used to analyze clinical data.
The levels of PTX-3 increased in the LCa groups.
PTX-3 levels were higher in the small cell lung cancer (SCLC) compared to non-small-cell lung cancer (NSCLC) groups.
In LCa patients, obstructive pneumonia could upregulate the expression of PTX-3 in BALF.
The area under the ROC curve of PTX-3 in BALF during LCa diagnosis, SCLC, and LCa with obstructive pneumonia was 0.949 (p≤0.001), 0.672 (p<0.05), and 0.838 (p<0.01), respectively.
In conclusion, PTX-3 in BALF has a potential value as an LCa biomarker, particularly in cases of SCLC and LCa with obstructive pneumonia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tantak, Nour& Omar, Ghefar& Ward, Fadi& Gennatas, Constantine& Chammout, Anwar& Ghabally, Mike…[et al.]. 2020. Pentraxin 3 (PTX-3) Levels in Bronchoalveolar Lavage Fluid as a Lung Cancer Biomarker. Disease Markers،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1153851
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tantak, Nour…[et al.]. Pentraxin 3 (PTX-3) Levels in Bronchoalveolar Lavage Fluid as a Lung Cancer Biomarker. Disease Markers No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1153851
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tantak, Nour& Omar, Ghefar& Ward, Fadi& Gennatas, Constantine& Chammout, Anwar& Ghabally, Mike…[et al.]. Pentraxin 3 (PTX-3) Levels in Bronchoalveolar Lavage Fluid as a Lung Cancer Biomarker. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1153851
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153851
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر