Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study
المؤلفون المشاركون
Shao, Yi
Ge, Qianmin
Wu, Shi-Nan
Zhang, Meng-Yao
Shu, Hui-Ye
Liang, Rong-Bin
Pan, Yi-Cong
Zhang, Li-Juan
Li, Qiu-Yu
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
In order to further study the changes of cerebral functional connectivity in patients with toothache (TA), this study used the resting-state functional magnetic resonance imaging (rs-fMRI) technique and degree centrality (DC) analysis method.
Methods.
Eighteen TA patients (8 males, 10 females) and 18 healthy individuals of similar age, sex, and educational levels were recruited as healthy controls (HCs) to take part in the study, and all underwent rs-fMRI examination.
And DC technology was used to compare the state of their cerebral spontaneous functional activity.
In order to compare the average DC values of the TA group and HC group, we used independent two-sample t-test and receiver operating characteristic (ROC) curve to compare the difference of DC values between the two groups, so as to distinguish the accuracy of TA diagnosis.
Finally, we also carry out Pearson’s linear regression analysis.
Results.
The TA group showed higher DC values in the right lingual gyrus (RLG), right precentral gyrus, and left middle temporal gyrus (LMTG) than HCs.
Moreover, ROC curve analysis indicated that the area under the curve (AUC) of each cerebral region studied had high accuracy.
In addition, linear analysis indicated that the DC values of the RLG were positively correlated with the Hospital Anxiety and Depression Scale (HADS) (r=0.844, p<0.001), and the DC values of the LMTG were positively correlated with the visual analogue scale (VAS) (r=0.723, p<0.001).
Conclusion.
TA generates abnormal changes in the intrinsic activity patterns of pain-related and vision-related areas of the cerebral cortex, which will be beneficial to reveal the underlying neuropathic mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Shi-Nan& Zhang, Meng-Yao& Shu, Hui-Ye& Liang, Rong-Bin& Ge, Qianmin& Pan, Yi-Cong…[et al.]. 2020. Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study. Disease Markers،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1153966
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Shi-Nan…[et al.]. Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study. Disease Markers No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1153966
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Shi-Nan& Zhang, Meng-Yao& Shu, Hui-Ye& Liang, Rong-Bin& Ge, Qianmin& Pan, Yi-Cong…[et al.]. Changes in Functional Connectivity of Specific Cerebral Regions in Patients with Toothache: A Resting-State Functional Magnetic Resonance Imaging Study. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1153966
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153966
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر