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Evidence of the Prognostic Value of Pretreatment Systemic Inflammation Response Index in Cancer Patients: A Pooled Analysis of 19 Cohort Studies
المؤلفون المشاركون
Liu, Fangteng
Zhang, Yi
Wang, Yang
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
Systemic inflammation response index (SIRI) is a new inflammation-based evaluation system that has been reported for predicting survival in multiple tumors, but the prognostic significance of SIRI in cancers has not been evinced.
Methods.
Eligible studies updated on December 31, 2019, were selected according to inclusion criteria, the literature searching was performed in PubMed, Web of Science, Google Scholar, and Cochrane.
Hazard ratios (HRs), and 95% confidence intervals (CIs) were extracted and pooled by using Stata/SE 14.1.
Results.
11 publications involving 19 cohort studies with a total of 5,605 subjects were included.
Meta-analysis results evinced that high SIRI was associated with worse OS (HR=2.30, 95% CI: 1.87-2.83, p≤0.001), poor CSS/DSS (HR=2.83, 95% CI: 1.98-4.04, p≤0.001), and inferior MFS/DFS/PFS/RFS/TTP (HR=1.88, 95% CI: 1.65-2.15, p≤0.001).
The association of SIRI with OS was not significantly affected when stratified by diverse confounding factors.
It was suggested that tumor patients with high pretreatment SIRI levels would suffer from adverse outcomes.
Conclusion.
High SIRI is associated with unfavorable clinical outcomes in human malignancies; pretreatment SIRI level might be a useful and promising predictive indicator of prognosis in cancers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Yi& Liu, Fangteng& Wang, Yang. 2020. Evidence of the Prognostic Value of Pretreatment Systemic Inflammation Response Index in Cancer Patients: A Pooled Analysis of 19 Cohort Studies. Disease Markers،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1154135
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Yi…[et al.]. Evidence of the Prognostic Value of Pretreatment Systemic Inflammation Response Index in Cancer Patients: A Pooled Analysis of 19 Cohort Studies. Disease Markers No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1154135
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Yi& Liu, Fangteng& Wang, Yang. Evidence of the Prognostic Value of Pretreatment Systemic Inflammation Response Index in Cancer Patients: A Pooled Analysis of 19 Cohort Studies. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1154135
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154135
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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