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Vitamin D Deficiency May Not Be an Independent Risk Factor for Peripheral Arterial Disease in Middle-Aged and Elderly Patients with Type 2 Diabetes in China
المؤلفون المشاركون
Feng, Tongbao
Lu, Kefeng
Zhou, Hongxing
Wang, Yan
Zhang, Ping
Bai, Yang
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-25
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Vitamin D deficiency can lead to the increased severity and prevalence of metabolic disorders.
However, the relationship between levels of 25-hydroxyvitamin D (25(OH)D) and peripheral arterial disease (PAD) is controversial.
Therefore, the purpose of our study was to explore the relationship between 25(OH)D levels and PAD in middle-aged and elderly type 2 diabetes mellitus (T2DM) patients in China.
Methods.
In this study, a total of 183 patients with T2DM were enrolled and categorized into groups with or without PAD.
Clinical and biochemical parameters were assessed, and a Pearson analysis was used to identify a possible association between levels of 25(OH)D and glycated hemoglobin (HbA1c).
Some biochemical parameters were also assessed in the T2DM patients with PAD according to vitamin D status.
Interactions were also explored among HbA1c control, 25(OH)D levels, and PAD.
The possible risk factors for PAD were measured by multivariable logistic regression analyses.
Results.
Firstly, the parameters including age, HbA1c, and disease duration between T2DM and T2DM+PAD groups showed significantly different.
In addition, the frequency of smoking in the group of T2DM patients was significantly less than that in the T2DM patients with the PAD group, while the frequency of well-controlled HbA1c in the patients with T2DM was significantly higher.
There is a trend that the levels of 25(OH)D and HbA1c are correlated, but no interactions among vitamin D deficiency, HbA1c control, and PAD were found.
However, HbA1c significantly differed between groups with vitamin D deficiency and insufficiency in the T2DM patients with PAD.
According to the multivariate logistic regression analyses, the PAD risk factors of T2DM patients were family history of diabetes, smoking, age, disease duration, HbA1c, and LDL.
Conclusions.
The findings demonstrate that the deficiency of vitamin D level is not related to PAD, but HbA1c may be linked to the presence of PAD in middle-aged and elderly patients with T2DM in China.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Yan& Feng, Tongbao& Zhou, Hongxing& Lu, Kefeng& Bai, Yang& Zhang, Ping. 2020. Vitamin D Deficiency May Not Be an Independent Risk Factor for Peripheral Arterial Disease in Middle-Aged and Elderly Patients with Type 2 Diabetes in China. Disease Markers،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154139
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Yan…[et al.]. Vitamin D Deficiency May Not Be an Independent Risk Factor for Peripheral Arterial Disease in Middle-Aged and Elderly Patients with Type 2 Diabetes in China. Disease Markers No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1154139
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Yan& Feng, Tongbao& Zhou, Hongxing& Lu, Kefeng& Bai, Yang& Zhang, Ping. Vitamin D Deficiency May Not Be an Independent Risk Factor for Peripheral Arterial Disease in Middle-Aged and Elderly Patients with Type 2 Diabetes in China. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154139
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154139
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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