Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats
المؤلفون المشاركون
Li, Xue-Li
Yang, Li-Na
Huang, Wen-Kai
Bai, Yu-Zuo
Zhang, Shu-Cheng
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
Neural crest stem cells (NCSCs) are prototypically migratory cells immigrating from the dorsal neural tube to specific embryonic sites where they generate a variety of cell types.
A lot of biomarkers for NCSCs have been identified.
However, which biomarkers are the most specific is still unclear.
Methods.
The rat embryos harvested in embryonic day 9 (E9), E9.5, E10, E10.5, E11, E12, E13, and E14 were paraffin-embedded and sectioned in transverse.
NCSCs were spatiotemporally demonstrated by immunohistochemical staining with RET, p75NTR, Pax7, and Sox10.
NCSCs were isolated, cultured, and stained with RET, p75NTR, Pax7, and Sox10.
Results.
In the paraffin sections of rat embryos, the immunohistochemical staining of RET, p75NTR, and Sox10 can all be used in demonstrating NCSCs.
Sox10 was positive mainly in NCSCs while RET and p75NTR were positive not only in NCSCs but also in other tissue cells.
In primary culture cells, Sox10 was mainly in the nucleus of NCSCs, RET was mainly in the membrane, and p75NTR was positive in cytoplasm and membrane.
Conclusions.
Sox10 is the specific marker for immunohistochemical staining of NCSCs in paraffin sections.
In cultured cells, Sox10, p75NTR, and RET presented a similar staining effect.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Li-Na& Huang, Wen-Kai& Li, Xue-Li& Bai, Yu-Zuo& Zhang, Shu-Cheng. 2020. Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats. Disease Markers،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154188
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Li-Na…[et al.]. Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats. Disease Markers No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1154188
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Li-Na& Huang, Wen-Kai& Li, Xue-Li& Bai, Yu-Zuo& Zhang, Shu-Cheng. Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154188
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154188
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر