Effect of Traditional Chinese Medicine Product, QiangGuYin, on Bone Mineral Density and Bone Turnover in Chinese Postmenopausal Osteoporosis
المؤلفون المشاركون
Shi, Zhen-Yu
Zhang, Xin-Gen
Li, Chun-Wen
Liu, Kang
Liang, Bo-Cheng
Shi, Xiao-Lin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
The aim of this study was to investigate the efficacy of herbal formula QiangGuYin (QGY) in postmenopausal women.
Materials and Methods.
A total of 240 participants from six clinical centers were randomly to receive alendronate 70 mg/week, QGY granules 20 g/day, and placebo.
Primary end points were BMD changes over 6 and 12 months; secondary end points were bone turnover markers changes at 3, 6, 9, and 12 months.
Safety was monitored by clinical adverse events reported during the follow-up.
Results.
Of 240 women recruited, 218 completed the study.
Significant BMD increases from baseline were observed over 6 and 12 months at each observed part both in QGY and alendronate compared with placebo (p<0.01).
Alendronate-treated subjects had significant decreases in β-CTX compared to QGY-treated subjects at each time point assessed (p<0.01).
Reduction in t-P1NP was only observed in the QGY group at 3 and 6 months (−23.81% and −3.07%, resp.).
No significant difference was observed in the overall incidence of clinical adverse events among the alendronate group and the QGY group (5.0% versus 7.5%, p=0.513).
Conclusion.
1-Year treatment with QGY demonstrated a safe statistical increase in BMD and new balance may be rebuilt after 9 months.
This trail is registered with ChiCTR-POC-16008026.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shi, Zhen-Yu& Zhang, Xin-Gen& Li, Chun-Wen& Liu, Kang& Liang, Bo-Cheng& Shi, Xiao-Lin. 2017. Effect of Traditional Chinese Medicine Product, QiangGuYin, on Bone Mineral Density and Bone Turnover in Chinese Postmenopausal Osteoporosis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154192
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shi, Zhen-Yu…[et al.]. Effect of Traditional Chinese Medicine Product, QiangGuYin, on Bone Mineral Density and Bone Turnover in Chinese Postmenopausal Osteoporosis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1154192
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shi, Zhen-Yu& Zhang, Xin-Gen& Li, Chun-Wen& Liu, Kang& Liang, Bo-Cheng& Shi, Xiao-Lin. Effect of Traditional Chinese Medicine Product, QiangGuYin, on Bone Mineral Density and Bone Turnover in Chinese Postmenopausal Osteoporosis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154192
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154192
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر