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Hepatoprotective Effects of Chinese Medicine Herbs Decoction on Liver Cirrhosis in Rats
المؤلفون المشاركون
Mat-Rahim, Nor Aziyah
Lim, Tong-Hye
Nor-Amdan, Nur-Asyura
Abu Bakar, Sazaly
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Hepatoprotective and curative activities of aqueous extract of decoction containing 10 Chinese medicinal herbs (HPE-XA-08) were evaluated in Sprague–Dawley albino rats with liver damage induced by thioacetamide (TAA).
These activities were assessed by investigating the liver enzymes level and also histopathology investigation.
Increases in alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) levels were observed in rats with cirrhotic liver.
No significant alterations of the liver enzymes were observed following treatment with HPE-XA-08.
Histopathology examination of rats treated with HPE-XA-08 at 250 mg/kg body weight, however, exhibited moderate liver protective effects.
Reduced extracellular matrix (ECM) proteins within the hepatocytes were noted in comparison to the cirrhotic liver.
The curative effects of HPE-XA-08 were observed with marked decrease in the level of ALP (more than 3x) and level of GGT (more than 2x) in cirrhotic rat treated with 600 mg/kg body weight HPE-XA-08 in comparison to cirrhotic rat treated with just water diluent.
Reversion of cirrhotic liver to normal liver condition in rats treated with HPE-XA-08 was observed.
Results from the present study suggest that HPE-XA-08 treatment assisted in the protection from liver cirrhosis and improved the recovery of cirrhotic liver.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mat-Rahim, Nor Aziyah& Lim, Tong-Hye& Nor-Amdan, Nur-Asyura& Abu Bakar, Sazaly. 2017. Hepatoprotective Effects of Chinese Medicine Herbs Decoction on Liver Cirrhosis in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1154218
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mat-Rahim, Nor Aziyah…[et al.]. Hepatoprotective Effects of Chinese Medicine Herbs Decoction on Liver Cirrhosis in Rats. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1154218
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mat-Rahim, Nor Aziyah& Lim, Tong-Hye& Nor-Amdan, Nur-Asyura& Abu Bakar, Sazaly. Hepatoprotective Effects of Chinese Medicine Herbs Decoction on Liver Cirrhosis in Rats. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1154218
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154218
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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