Plasma Adipokines in Patients Resuscitated from Cardiac Arrest: Difference of Visfatin between Survivors and Nonsurvivors
المؤلفون المشاركون
Zhuang, Yugang
Chen, Yuan-Zhuo
Zhou, Shu-Qin
Chen, Yan-Qing
Peng, Hu
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-17
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Adipokines are a group of cytokines or peptides secreted by adipose tissue to exert numerous biological functions.
In the present study, we measured the plasma levels of four adipokines (adiponectin, leptin, fatty acid-binding protein 4 (FABP4), and visfatin) in cardiac arrest patients following return of spontaneous circulation (ROSC).
Methods.
Totally, 21 patients who experienced cardiac arrest and successful ROSC with expected survival of at least 48 hours (from January 2016 to December 2017) were consecutively enrolled into this prospective observational clinical study.
Of the 21 enrolled patients, ten survived, and other eleven died between 2 days and 6 months post ROSC.
Venous blood was drawn at three time points: baseline (<1 hour post ROSC), 2 days post ROSC, and 7 days post ROSC.
Plasma concentrations of adiponectin, leptin, FABP4, and visfatin were determined using commercial enzyme-linked immunosorbent assays.
Results.
The plasma visfatin levels at 2 or 7 days post ROSC increased significantly compared with the baseline (P<0.01), while plasma levels of adiponectin, leptin, and FABP4 did not change.
Moreover, plasma visfatin levels in survivors at 2 or 7 days post ROSC were higher than those in nonsurvivors (P<0.01).
Plasma visfatin levels at 2 or 7 days post ROSC were negatively correlated with Acute Physiology and Chronic Health Evaluation (APACHE) II score and time to ROSC.
Moreover, receiver operating characteristic curve analysis showed that the plasma visfatin levels at 2 or 7 days post ROSC were good predictors for survival of the patients.
Conclusion.
Elevated plasma visfatin levels may be a marker for better outcome of cardiac arrest patients post ROSC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Yuan-Zhuo& Zhou, Shu-Qin& Chen, Yan-Qing& Peng, Hu& Zhuang, Yugang. 2020. Plasma Adipokines in Patients Resuscitated from Cardiac Arrest: Difference of Visfatin between Survivors and Nonsurvivors. Disease Markers،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1154228
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Yuan-Zhuo…[et al.]. Plasma Adipokines in Patients Resuscitated from Cardiac Arrest: Difference of Visfatin between Survivors and Nonsurvivors. Disease Markers No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1154228
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Yuan-Zhuo& Zhou, Shu-Qin& Chen, Yan-Qing& Peng, Hu& Zhuang, Yugang. Plasma Adipokines in Patients Resuscitated from Cardiac Arrest: Difference of Visfatin between Survivors and Nonsurvivors. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1154228
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154228
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر