Self-Reported Antidepressant Drug Side Effects, Medication Adherence, and Its Associated Factors among Patients Diagnosed with Depression at the Psychiatric Hospital of Nepal
المؤلفون المشاركون
Sankhi, Sabina
Marasine, Nirmal Raj
Dangi, Nim Bahadur
Lamichhane, Rajendra
Marasini, Nabin Raj
المصدر
Depression Research and Treatment
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-20
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
The present study is aimed at evaluating the side effects of antidepressant drugs, medication adherence (MA), and associated factors among patients diagnosed with depression at a psychiatric hospital in western Nepal.
Methods.
A prospective cross-sectional study was conducted among 174 patients visiting the outpatient clinic of a psychiatric hospital.
The antidepressant side effect checklist (ASEC) was used to classify the reported antidepressant drug side effects into mild, moderate, and severe types.
The Naranjo adverse drug reaction (ADR) probability scale was employed to assess the ADRs, and the Morisky Green Levine Adherence (MGLA) score was employed to determine the rate of medication adherence.
Descriptive statistics and bivariate analysis were used, and a P value < 0.05 was taken as statistically significant in the multivariate analysis.
Results.
The patients were mostly female (55.74%), with a median (IQR) age of 32 (20) years.
Approximately 74.13% of the patients experienced antidepressant side effects, where insomnia (17.05%) and anxiety (17.05%) were the most common.
More than half of the patients (52.29%) had a low level of adherence.
Females were 1.01 times more likely to be nonadherent to their antidepressant medications compared to males, adjusted odds ratio (AOR): 1.001 (0.31-1.63).
Similarly, illiterate patients tended to be more nonadherent compared to literates, AOR: 1.342 (0.
93-2.82), and unemployed individuals were 1.5 times more likely to be nonadherent to their medications compared to employed individuals, AOR: 1.46 (1.16-4.13).
Likewise, patients with severe side effects were more prone to develop nonadherence than those with moderate side effects, AOR: 1.173 (0.42-3.25).
A significant association was found between the Naranjo score and medication adherence.
Conclusions.
This study suggests that antidepressant drug side effects were more prevalent and medication adherence was extremely poor among depressive patients in psychiatric hospitals.
Factors such as gender, occupation, education, side effects, and ADRs attributed to poor medication adherence in patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Marasine, Nirmal Raj& Sankhi, Sabina& Lamichhane, Rajendra& Marasini, Nabin Raj& Dangi, Nim Bahadur. 2020. Self-Reported Antidepressant Drug Side Effects, Medication Adherence, and Its Associated Factors among Patients Diagnosed with Depression at the Psychiatric Hospital of Nepal. Depression Research and Treatment،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154386
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Marasine, Nirmal Raj…[et al.]. Self-Reported Antidepressant Drug Side Effects, Medication Adherence, and Its Associated Factors among Patients Diagnosed with Depression at the Psychiatric Hospital of Nepal. Depression Research and Treatment No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1154386
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Marasine, Nirmal Raj& Sankhi, Sabina& Lamichhane, Rajendra& Marasini, Nabin Raj& Dangi, Nim Bahadur. Self-Reported Antidepressant Drug Side Effects, Medication Adherence, and Its Associated Factors among Patients Diagnosed with Depression at the Psychiatric Hospital of Nepal. Depression Research and Treatment. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154386
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154386
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر