Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response
المؤلفون المشاركون
Cuman, Roberto Kenji Nakamura
Silva, Expedito Leite
Silva-Filho, Saulo Euclides
Cardia, Gabriel Fernando Esteves
Uchida, Nancy Sayuri
Cavalcante, Heitor Augusto Otaviano
Cassarotti, Larissa Laila
Salvadego, Valter Eduardo Cocco
Spironello, Ricardo Alexandre
Bersani-Amado, Ciomar Aparecida
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-18
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Lavandula angustifolia is a plant of Lamiaceae family, with many therapeutic properties and biological activities, such as anticonvulsant, anxiolytic, antioxidant, anti-inflammatory, and antimicrobial activities.
The aim of this study was to evaluate the effect of Lavandula angustifolia Mill.
essential oil (LEO) on acute inflammatory response.
LEO was analyzed using gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance spectroscopy (NMR) methods and showed predominance of 1,8-cineole (39.83%), borneol (22.63%), and camphor (22.12%).
LEO at concentrations of 0.5, 1, 3, and 10 μg/ml did not present in vitro cytotoxicity.
Additionally, LEO did not stimulate the leukocyte chemotaxis in vitro.
The LEO topical application at concentrations of 0.25, 0.5, and 1 mg/ear reduced edema formation, myeloperoxidase (MPO) activity, and nitric oxide (NO) production in croton oil-induced ear edema model.
In carrageenan-induced paw edema model, LEO treatment at doses of 75, 100, and 250 mg/kg reduced edema formation, MPO activity, and NO production.
In dextran-induced paw edema model, LEO at doses of 75 and 100 mg/kg reduced paw edema and MPO activity.
In conclusion, LEO presented anti-inflammatory activity, and the mechanism proposed of LEO seems to be, at least in part, involving the participation of prostanoids, NO, proinflammatory cytokines, and histamine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cardia, Gabriel Fernando Esteves& Silva-Filho, Saulo Euclides& Silva, Expedito Leite& Uchida, Nancy Sayuri& Cavalcante, Heitor Augusto Otaviano& Cassarotti, Larissa Laila…[et al.]. 2018. Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154397
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cardia, Gabriel Fernando Esteves…[et al.]. Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1154397
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cardia, Gabriel Fernando Esteves& Silva-Filho, Saulo Euclides& Silva, Expedito Leite& Uchida, Nancy Sayuri& Cavalcante, Heitor Augusto Otaviano& Cassarotti, Larissa Laila…[et al.]. Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154397
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154397
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر