Therapeutic Effectiveness of Galphimia glauca in Young People with Social Anxiety Disorder: A Pilot Study
المؤلفون المشاركون
Zamilpa, Alejandro
Tortoriello, Jaime
Romero-Cerecero, Ofelia
Islas-Garduño, Ana Laura
Pérez-García, Ma. Dolores
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-09-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Social anxiety is one of the most common disorders found in the population attending the first level of health care.
Galphimia glauca has been used for many years in Mexican traditional medicine to treat “nervous disorders”.
A standardized extract of this species has been evaluated in clinical studies that have proven its efficacy and safety in patients with generalized anxiety disorder.
In this work, a double-blind clinical trial was carried out, using sertraline as a control.
Patients from both sexes (18 to 35 years old) with moderate or severe social anxiety were included.
Experimental group was treated daily (orally), for 10 weeks, with an extract from G.
glauca containing 0.374 mg/dose of Galphimine-B (G-B, active compound).
Patients in the control group were given sertraline (50 mg) in the same conditions.
All patients were evaluated every two weeks.
Another assessment was done one month after the end of the administration period.
A total of 34 patients was included, 17 in each group.
Women were predominant, and the mean age was 25 ± 4.7 years.
In patients who received the G.
glauca standardized extract, a significant reduction in anxiety was observed, with a value (in the Brief Social Phobia Scale) of 41.1±10.3 points at the start and 11.2±5.6 points at the end of treatment, while patients treated with sertraline had a value of 37.7±7.3 points at the beginning and 11.1±5.2 points at the end.
No significant difference was observed between the treated groups.
In a similar way, the health scale showed a gradual and continuous improvement in each of the five evaluations.
In conclusion, the 10-week oral administration of G.
glauca standardized extract showed efficacy and safety in patients with social anxiety disorder, without showing a significant difference from patients treated with sertraline.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Romero-Cerecero, Ofelia& Islas-Garduño, Ana Laura& Zamilpa, Alejandro& Pérez-García, Ma. Dolores& Tortoriello, Jaime. 2018. Therapeutic Effectiveness of Galphimia glauca in Young People with Social Anxiety Disorder: A Pilot Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1154460
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Romero-Cerecero, Ofelia…[et al.]. Therapeutic Effectiveness of Galphimia glauca in Young People with Social Anxiety Disorder: A Pilot Study. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1154460
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Romero-Cerecero, Ofelia& Islas-Garduño, Ana Laura& Zamilpa, Alejandro& Pérez-García, Ma. Dolores& Tortoriello, Jaime. Therapeutic Effectiveness of Galphimia glauca in Young People with Social Anxiety Disorder: A Pilot Study. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1154460
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154460
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر