Investigation on the Antibacterial and Anti-T3SS Activity of Traditional Myanmar Medicinal Plants
المؤلفون المشاركون
Li, Tianhong
Zhang, Dongdong
Oo, Thaung Naing
San, Myint Myint
Mon, Aye Mya
Hein, Pyae Phyo
Wang, Yuehu
Lu, Chunhua
Yang, Xuefei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-09
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Myanmar has a rich pool of, but less known, medicinal plants with traditional knowledge.
In this study, we aimed to investigate the inhibitory activity of traditional Myanmar medicinal plants against the type III secretion system (T3SS) of Salmonella enterica serovar Typhimurium UK-1 χ8956 and the intestinal disease-caused by microbes including S.
enterica serovar Typhimurium UK-1 χ8956, Proteusbacillus vulgaris CPCC 160013, Escherichia coli CICC 10003, and Staphylococcus aureus ATCC 25923.
The EtOH extracts of 93 samples were used to screen the inhibitory activities against the secretion of T3SS effector proteins SipA/B/C/D of S.
enterica and the antibacterial activity against S.
enterica, P.
vulgaris, E.
coli, and S.
aureus.
Out of 71 crude drugs traditionally used, 18 were proofed to be effective either on the growth inhibition of tested bacteria and/or as inhibitors for the T3SS.
The EtOH extracts of five plants, Luvunga scandens (Roxb.) Buch.-Ham.
ex Wight & Arn.
(My7), Myrica nagi Thunb.
(My11), Terminalia citrina Roxb.
ex Fleming (My21), Thymus vulgaris L.
(My49), and Cinnamomum bejolghota (Buch.-Ham.) Sweet (My104), showed potent inhibitory activities against the secretion of T3SS proteins SipA/B/C/D of S.
enterica serovar Typhimurium UK-1 χ 8956.
Mansonia gagei J.R.Drumm (My3) and Mesua ferrea (Roxb.) L.
(My10) showed strong antibacterial activities against P.
vulgaris and S.
aureus.
This study provided the first scientific evidence of T3SS prohibiting and antibacterial properties for the traditional knowledge in Myanmar of using plants as medicines for treating infections and gastrointestinal disease.
Further researches are proposed to discover the active chemical compounds and mechanism of L.
scandens (Roxb.) Buch.-Ham.
ex Wight & Arn, M.
nagi Thunb., T.
citrina Roxb.
ex Fleming, T.
vulgaris L., and C.
bejolghota (Buch.-Ham.) Sweet as antivirulence drugs and the potential of M.
gagei J.R.Drumm and M.
ferrea L.
as new broad spectrum plant antibiotics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Tianhong& Zhang, Dongdong& Oo, Thaung Naing& San, Myint Myint& Mon, Aye Mya& Hein, Pyae Phyo…[et al.]. 2018. Investigation on the Antibacterial and Anti-T3SS Activity of Traditional Myanmar Medicinal Plants. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154678
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Tianhong…[et al.]. Investigation on the Antibacterial and Anti-T3SS Activity of Traditional Myanmar Medicinal Plants. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1154678
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Tianhong& Zhang, Dongdong& Oo, Thaung Naing& San, Myint Myint& Mon, Aye Mya& Hein, Pyae Phyo…[et al.]. Investigation on the Antibacterial and Anti-T3SS Activity of Traditional Myanmar Medicinal Plants. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154678
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154678
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر